Home › Studies › PRJDB13214
PRJDB13214 DRP009646

Gut microbiome in COVID-19 patients, Japan, cross-sectional

The characteristics of gut microbiome in COVID-19 patients

Cross-sectional study of 208 gut metagenome samples from Japan, comparing COVID-19/other-infection samples (103) with healthy controls (105) to characterize gut microbiome features. machine-written summary

208 samples · 208 runs · JP · Age unknown · 2023 · 6.41 Gbp / sample

Sources
✓Sequence archive 624○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive624 sample values (country, health condition, health condition detail)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown208
Condition
healthy_control105
other_infection103
Country
JP208
Body site
primary208
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 2 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 191 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 14 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)this project, 30–100 Gbp: 1 samplesall projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.41 Gbp per sample0130Gbp
Community composition
Blautia_A 9.1%Bifidobacterium 9.0%Mediterraneibacter 6.6%Streptococcus 4.7%Collinsella 4.5%Faecalibacterium 3.9%Bacteroides 3.7%Roseburia 3.4%Fusicatenibacter 2.8%Gemmiger 2.5%Escherichia 2.5%Phocaeicola 2.3%not assigned to a genus 3.7%other genera 41.4%

Genera, mean relative abundance over 189 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country208 100%208
health_condition208 100%208
subject_id0 0%
health_condition_detail208 100%208
Papers (1)
  • Deciphering Microbial Shifts in the Gut and Lung Microbiomes of COVID-19 Patients. 2024 PMID 38930440 PMC11205787 unsure
Details
Archive description

We aim to investigate the characteristics of gut microbiome in COVID-19 patients in Japan by performing the metagenomic analysis.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.82. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • host run.scientific_name · “human gut metagenome”
  • body site study.title · “gut microbiome in COVID-19 patients”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMD00447339countryJPR10.90sample.attr.geo_loc_nameJapan
SAMD00447339health_conditionother_infectionR10.70sample.name_rule:titlegut microbiome of covid-19-1001
SAMD00447339health_condition_detailCOVID-19 patient (title literal 'gut microbiome of covid-19-XXXX'; project title/description: 'gut microbiome in COVID-19 patients')R10.70sample.name_rule:titlegut microbiome of covid-19-1001
Sequencing

208 runs over 208 samples · mean 7.03 Gbp per run (median 6.41 Gbp, total 1,462.42 Gbp; 208 runs with a base count) · layout PAIRED 208 · platform ILLUMINA 208 · models Illumina NovaSeq 6000 (208) · 91% of runs with a Sandpiper profile · first public 2023-03-04

Authors (5)

Pusadkar V first · Mazumder A · Azad A · Patil D · Azad RK last

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJDB13214.csv.gz (5.9 KB) · parquet (76.7 KB) — all 208 samples, every field with route and confidence · PRJDB13214_determinations.csv.gz (5.8 KB) — 624 evidence rows

Samples (208 · every field this project has values for · hover a cell for its source)
Loading the sample table…