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PRJDB14272 DRP017380

Gut metagenomes of ulcerative colitis patients in Japan

Metagenomic analysis of fecal samples obtained from ulcerative colitis patient in Japan

114 fecal samples from ulcerative colitis patients in Japan, studied in relation to antibiotic intervention; age and design details not specified. machine-written summary

114 samples · 114 runs · JP · Age unknown · 2026 · 0.16 Gbp / sample

Sources
✓Sequence archive 456✓Abstract / description 456–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive456 sample values (collection date, country, subject id, timepoint)
✓ Abstract / description456 sample values (antibiotic exposure, health condition, health condition detail, location region)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Antibiotic given as the study intervention (incl. eradication therapy design single_arm_before_after · population ulcerative_colitis · Antibiotic combination therapy for ulcerative colitis

“treated with antibiotic combination therapy” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 country
Age
unknown114
Condition
ulcerative_colitis114
Country
JP114
Body site
primary114
Collected 2012–2015
2012: 9 samples2013: 33 samples2014: 50 samples2015: 22 samples20122015
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 19 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 8 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 66 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 15 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 6 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.16 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

31 of 31 people sampled more than once (114 samples; median 4, up to 8 per person). Schedule stated by the source: “Sample names encode before/after status and a day offset per patient (e.g. before_-3, after_14, after_84, after_365); no fixed schedule text given.”.

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country114 100%114
health_condition114 100%114
subject_id114 100%114
antibiotic_exposure114 100%114
collection_date114 100%114
detailed_location114 100%
health_condition_detail114 100%114
location_region114 100%114
timepoint_label114 100%114
Details
Archive description

This project is related to metagenomic analysis of fecal samples obtained from ulcerative colitis patient in Japan treated with antibiotic combination therapy.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.75. Assay shotgun_dna.

  • host study.title · “obtained from ulcerative colitis patient in Japan”
  • body site study.title · “fecal samples”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMD00523986antibiotic_exposureyesR40.50study.descriptiontreated with antibiotic combination therapy
SAMD00523986collection_date2015R10.85biosample.attribute:collection_date2015
SAMD00523986countryJPR10.85biosample.attribute:geo_loc_nameJapan
SAMD00523986health_conditionulcerative_colitisR40.50study.titlefecal samples obtained from ulcerative colitis patient in Japan
SAMD00523986health_condition_detailUlcerative colitis patient(s) treated with antibiotic combination therapyR40.50study.descriptionulcerative colitis patient in Japan treated with antibiotic combination therapy
SAMD00523986location_regionJapanR40.45ena.study_descriptionfecal samples obtained from ulcerative colitis patient in Japan
SAMD00523986subject_idP-01R10.85biosample.attribute:host_subject_idP-01
SAMD00523986timepoint_labelbefore_0R10.70sample.name_rule:sample_nameP-01_1_before_0
Sequencing

114 runs over 114 samples · mean 0.25 Gbp per run (median 0.16 Gbp, total 28.42 Gbp; 114 runs with a base count) · layout SINGLE 114 · platform ILLUMINA 114 · models Illumina MiSeq (88), Illumina Genome Analyzer IIx (26) · 0% of runs with a Sandpiper profile · first public 2026-04-12

Authors (0)

No author record.

Downloads

PRJDB14272.csv.gz (3.7 KB) · parquet (74.6 KB) — all 114 samples, every field with route and confidence · PRJDB14272_determinations.csv.gz (7.5 KB) — 912 evidence rows

Samples (114 · every field this project has values for · hover a cell for its source)
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