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PRJDB37508 DRP013987

Gut metagenome in colorectal cancer patients, Tokyo, Japan

Human Gut Metagenome

Cross-sectional study of 470 fecal samples from Japanese colorectal cancer patients undergoing colonoscopy at the National Cancer Research Center in Tokyo, Japan. machine-written summary

470 samples · 470 runs · JP · Age unknown · 2025 · 6.39 Gbp / sample

Sources
✓Sequence archive 940✓Abstract / description 1,880–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive940 sample values (country, location region)
✓ Abstract / description1,880 sample values (health condition, health condition detail, location site, subject id)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown470
Condition
colorectal_cancer470
Country
JP470
Body site
primary470
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 1 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 2 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 14 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 429 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 24 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.39 Gbp per sample0130Gbp
Community composition
Phocaeicola 13.6%Prevotella 11.3%Bacteroides 10.1%Faecalibacterium 4.0%Roseburia 3.4%Parabacteroides 2.9%Alistipes 2.7%Mediterraneibacter 2.4%Lachnospira 2.1%Bifidobacterium 2.0%Blautia_A 1.7%Enterocloster 1.6%not assigned to a genus 4.6%other genera 37.7%

Genera, mean relative abundance over 453 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country470 100%470
health_condition470 100%470
subject_id470 100%470
detailed_location470 100%
health_condition_detail470 100%470
location_region470 100%470
location_site470 100%470
Details
Archive description

Total microbial community DNA was isolated from the fecal samples of Japanese patients who underwent colonoscopy at National Cancer Research Center. The study population contains subjects diagnosed with Colorectal Cancer.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.80. Assay shotgun_dna.

  • host study.description · “fecal samples of Japanese patients who underwent colonoscopy”
  • body site study.description · “Total microbial community DNA was isolated from the fecal samples”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMD01681025countryJPR10.90sample.attr.geo_loc_nameJapan:Tokyo
SAMD01681025health_conditioncolorectal_cancerR40.50study.descriptionsubjects diagnosed with Colorectal Cancer
SAMD01681025health_condition_detailColorectal CancerR40.50study.descriptionsubjects diagnosed with Colorectal Cancer
SAMD01681025location_regionTokyoR10.85biosample.attribute:geo_loc_nameJapan:Tokyo
SAMD01681025location_siteNational Cancer Research CenterR40.45ena.study_descriptioncolonoscopy at National Cancer Research Center
SAMD01681025subject_idSAMD01681025R40.60design.one_sample_per_subject:descriptionTotal microbial community DNA was isolated from the fecal samples of Japanese patients
Sequencing

470 runs over 470 samples · mean 6.60 Gbp per run (median 6.39 Gbp, total 3,099.79 Gbp; 470 runs with a base count) · layout PAIRED 470 · platform ILLUMINA 470 · models Illumina HiSeq 2500 (470) · 96% of runs with a Sandpiper profile · first public 2025-09-28

Authors (0)

No author record.

Downloads

PRJDB37508.csv.gz (12.7 KB) · parquet (89.2 KB) — all 470 samples, every field with route and confidence · PRJDB37508_determinations.csv.gz (13.8 KB) — 2,820 evidence rows

Samples (470 · every field this project has values for · hover a cell for its source)
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