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PRJDB38277 DRP015353

Gut microbiota of long-lived elderly, cross-sectional

Characteristics of intestinal bacteria in long-lived elderly (PRJCA019954)

Cross-sectional study of 51 gut microbiome samples from long-lived elderly individuals, examining bacterial structure and function and their correlation with clinical indicators related to longevity and healthy ageing. Sample location not reported. machine-written summary

51 samples · 51 runs · Elderly · 2025 · 6.38 Gbp / sample

Sources
✓Sequence archive 51○Abstract / description✓Full text 153○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive51 sample values (collection date)
○ Abstract / descriptionread; no usable statement
✓ Full text153 sample values (antibiotic exposure, location site, subject id) · PMC12298205
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
Age
elderly51
Body site
primary51
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 51 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.38 Gbp per sample0130Gbp
Community composition
Bacteroides 13.1%Phocaeicola 11.6%Prevotella 8.7%Faecalibacterium 4.4%Escherichia 4.1%Alistipes 4.1%Roseburia 3.1%Lachnospira 2.5%Mediterraneibacter 2.2%Ruminococcoides 2.2%Hominimerdicola 2.0%Bifidobacterium 1.9%not assigned to a genus 5.8%other genera 34.3%

Genera, mean relative abundance over 50 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category51 100%
country0 0%
health_condition0 0%
subject_id51 100%51
antibiotic_exposure51 100%51
collection_date51 100%51
detailed_location51 100%
location_site51 100%51
Papers (1)
Details
Archive description

This project aims to explore the characteristics of bacterial structure and function in long-lived individuals, as well as the correlation of between bacteria and clinical indicators, in order to discover intestinal bacteria and functional pathways closely related to longevity and healthy ageing.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of elderly by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_unknown_no_evidence”
  • body site study.title · “Characteristics of intestinal bacteria in long-lived”
  • body site study.description · “order to discover intestinal bacteria and functional”
  • life stage study.title · “intestinal bacteria in long-lived elderly (PRJCA019954)”
  • life stage study.description · “and function in long-lived individuals, as well”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMD01708910antibiotic_exposurenoR30.70paper.body.textno treatment with antibiotics or probiotics within 1 month before sample collection
SAMD01708910collection_date2022-01-05R10.90biosample.attribute:collection_date2022-01-05
SAMD01708910location_sitePeking University People's HospitalR30.70paper.body.textcontinuously recruited at the geriatric department of Peking University People’s Hospital
SAMD01708910subject_idSAMD01708910R30.70design.one_sample_per_subject:fulltextFifty-one older adults aged ≥ 60 years (including 27 participants aged 90 years and above) were enrolled
Sequencing

51 runs over 51 samples · mean 6.36 Gbp per run (median 6.38 Gbp, total 324.36 Gbp; 51 runs with a base count) · layout PAIRED 51 · platform ILLUMINA 51 · models Illumina NovaSeq 6000 (51) · 98% of runs with a Sandpiper profile · first public 2025-12-21

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: country, health_condition. Share metadata

Downloads

PRJDB38277.csv.gz (2.4 KB) · parquet (71.6 KB) — all 51 samples, every field with route and confidence · PRJDB38277_determinations.csv.gz (2.3 KB) — 204 evidence rows

Samples (51 · every field this project has values for · hover a cell for its source)
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