Han Chinese Gut Microbiome Reference Genome Catalog
A cross-sectional study of 1,145 gut microbiome samples used to build a reference genome catalog representing the Han Chinese population, addressing underrepresentation of non-Western populations in existing catalogs. machine-written summary
1,146 samples · 1,170 runs · CN · Age unknown · 2026 · 8.44 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,146 sample values (collection date) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC12895597 |
| ✓ Supplementary tables | 2,283 sample values (country, location region) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 1,146 | 100% | 1,146 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% | ||||
| collection_date | 1,146 | 100% | 1,146 | |||
| detailed_location | 1,137 | 99% | ||||
| location_region | 1,137 | 99% | 1,137 |
- Exploring Population Differences in the Human Gut Microbiome: from Microbial Abundance to Single Nucleotide Polymorphisms 2025 own_data
- Exploring differences in the human gut microbiome between Han Chinese and non-Chinese populations. 2026 PMID 41545888 PMC12895597 own_data
Archive description
The gut microbiota exhibits population-specific variations influenced by host genetics, diet, and lifestyle, yet prior studies have largely overlooked microbial genomic diversity due to limited reference genomes. Most catalogs are biased toward Western populations, lacking robust representation of the Han Chinese population, which displays significant regional dietary and lifestyle diversity. To address this, we constructed a high-quality gut reference genome catalog.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.70. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- host study.title · “Human Gut Microbiome”
- body site run.scientific_name · “human gut metagenome”
- body site study.title · “Human Gut Microbiome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMD01709126 | collection_date | 2021-01-01 | R1 | 0.90 | biosample.attribute:collection_date | 2021-01-01 |
| SAMD01709126 | country | CN | R2 | 0.80 | paper.supp.13059_2026_3932_MOESM1_ESM.xlsx[Table S1!Country] | Breast_17112475 China |
| SAMD01709126 | location_region | Guangdong | R2 | 0.80 | paper.supp.13059_2026_3932_MOESM1_ESM.xlsx[Table S1!Province] | Breast_17112475 Guangdong |
Sequencing
1,170 runs over 1,146 samples · mean 8.47 Gbp per run (median 8.42 Gbp, total 9,904.74 Gbp; 1,170 runs with a base count) · layout PAIRED 1,170 · platform BGISEQ 1,170 · models MGISEQ-2000RS (1,170) · 0% of runs with a Sandpiper profile · first public 2026-06-02 – 2026-09-03
Authors (0)
No author record.
Help complete this project
3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata
Downloads
PRJDB38712.csv.gz (24.5 KB) · parquet (109.8 KB) — all 1,146 samples, every field with route and confidence · PRJDB38712_determinations.csv.gz (22.7 KB) — 3,429 evidence rows