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PRJDB7378 DRP005644

Gut metagenome in Japanese colonoscopy patients, cross-sectional

Generic sample from human gut metagenome

50 fecal metagenome samples from Japanese patients who underwent colonoscopy at National Cancer Research Center, including healthy individuals and those with gastrectomy; cross-sectional design. machine-written summary

50 samples · 50 runs · JP · Age unknown · 2019 · 6.61 Gbp / sample

Sources
✓Sequence archive 210✓Abstract / description 100○Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive210 sample values (collection date, country, latitude, location region, longitude)
✓ Abstract / description100 sample values (health condition detail, location site)
○ Full textread; no usable statement or table · PMC11402979, PMC7398469
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown50
Country
JP50
Body site
primary50
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 1 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 48 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.61 Gbp per sample0130Gbp
Community composition
Prevotella 16.7%Phocaeicola 8.9%Bacteroides 7.6%Streptococcus 4.4%Roseburia 4.2%Escherichia 3.8%Faecalibacterium 3.7%Lachnospira 2.7%Klebsiella 2.3%Alistipes 2.2%Parabacteroides 1.8%Blautia_A 1.5%not assigned to a genus 4.5%other genera 35.7%

Genera, mean relative abundance over 42 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country50 100%50
health_condition0 0%
subject_id0 0%
collection_date50 100%50
detailed_location50 100%
health_condition_detail50 100%50
latitude50 100%50
location_site50 100%50
longitude50 100%50
location_region10 20%10
Papers (2)
  • An expanded database and analytical toolkit for identifying bacterial virulence factors and their associations with chronic diseases. 2024 PMID 39278950 PMC11402979 cites_accession
  • Influence of gastrectomy for gastric cancer treatment on faecal microbiome and metabolome profiles. 2020 PMID 31953253 PMC7398469 own_data
Details
Archive description

Total microbial community DNA was isolated from the fecal samples of Japanese patients who underwent colonoscopy at National Cancer Research Center. The study population contains health, gastrectomy.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.68. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.description · “fecal samples of Japanese patients”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMD00136647collection_date2014R10.90biosample.attribute:collection_date2014
SAMD00136647countryJPR10.90sample.attr.geo_loc_nameJapan
SAMD00136647health_condition_detailmixed_case_control: healthy subjects and gastrectomy patientsR40.40study.descriptionhealth, gastrectomy
SAMD00136647latitude35.6600R10.90biosample.attribute:lat_lon35.66 N 139.76 E
SAMD00136649location_regionTokyoR10.60biosample.attribute:lat_lon35.66 N 139.78 E
SAMD00136647location_siteNational Cancer Research CenterR40.45ena.study_descriptioncolonoscopy at National Cancer Research Center
SAMD00136647longitude139.7600R10.90biosample.attribute:lat_lon35.66 N 139.76 E
Sequencing

50 runs over 50 samples · mean 6.78 Gbp per run (median 6.61 Gbp, total 339.06 Gbp; 50 runs with a base count) · layout PAIRED 50 · platform ILLUMINA 50 · models Illumina HiSeq 2500 (50) · 84% of runs with a Sandpiper profile · first public 2019-12-09

Authors (0)

No author record.

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJDB7378.csv.gz (2.2 KB) · parquet (71.8 KB) — all 50 samples, every field with route and confidence · PRJDB7378_determinations.csv.gz (2.4 KB) — 310 evidence rows

Samples (50 · every field this project has values for · hover a cell for its source)
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