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PRJEB100868 ERP182314

Infant gut microbiota development in Sweden (PREVENT 1)

PREVENT 1: Gut microbiota development and health in early life

744 stool samples from Swedish infants (0–12 months) in a longitudinal cohort study linking gut microbiota development to family health and lifestyle questionnaires. machine-written summary

744 samples · 744 runs · SE · Infant / toddler · 2026 · 9.52 Gbp / sample

Sources
✓Sequence archive 744○Abstract / description✓Full text 744–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive744 sample values (country)
○ Abstract / descriptionread; no usable statement
✓ Full text744 sample values (preterm status)
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
infant744
Country
SE744
Body site
primary744
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 430 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 314 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 9.52 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category744 100%
country744 100%744
health_condition0 0%
subject_id0 0%
preterm_status744 100%744
Papers (1)
  • (no title) curated
Details
Archive description

In this research study (PREVENT 1), Alba Health, in collaboration with academic institutions (Uppsala University, COPSAC and University of Antwerp) is investigating the association between the developing gut microbiota (collection of microbes present in the human gut) in the first year of life and lifestyle, wellbeing and health in a Swedish population. The study is the first of its kind in a Swedish population to collect and associate microbiome composition to an extensive family history and health questionnaire, stool colour and crying type, building on learnings from previous studies performed in other countries, such as the HELMI and COPSAC studies (HELMI - Finnish Health and Early Life Microbiota cohort from the University of Helsinki in Finland COPSAC - Copenhagen Prospective Studies on Asthma in Childhood in Denmark). The PREVENT 1 study is an observational research study led by Alba Health involving 300 families in Sweden with children between 0 and 12 months of age at the time of the study's start. After providing informed consent, the participating families will be asked to provide three stool samples from their child (the sample collection is not invasive and does not cause discomfort) and will be asked to answer questionnaires on lifestyle, well-being, and family health. The participating families will not be asked to change their lifestyle beyond sample and data collection.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler and child by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site study.title · “PREVENT 1: Gut microbiota development and”
  • body site study.description · “between the developing gut microbiota (collection of”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
  • life stage study.title · “and health in early life”
  • life stage study.description · “on Asthma in Childhood in Denmark). The”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA120416656countrySER10.90biosample_attrSweden
SAMEA120416656preterm_statustermR30.80paper.fulltext.resultsterm-born newborns (up to 12 months)
Sequencing

744 runs over 744 samples · mean 10.07 Gbp per run (median 9.52 Gbp, total 7,488.56 Gbp; 744 runs with a base count) · layout PAIRED 744 · platform ILLUMINA 744 · models Illumina NovaSeq X (744) · 0% of runs with a Sandpiper profile · first public 2026-06-29

Authors (7)

Cavani E first · Edbom Devall A · Chen Y · Grompone G · Brusselaers N · Vlajic M · de Vos WM last

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJEB100868.csv.gz (18.4 KB) · parquet (99.9 KB) — all 744 samples, every field with route and confidence · PRJEB100868_determinations.csv.gz (4.6 KB) — 1,488 evidence rows

Samples (744 · every field this project has values for · hover a cell for its source)
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