Home › Studies › PRJEB101120
PRJEB101120 ERP182549

Atopic dermatitis gut metagenomics in Tanzania & Switzerland

Metagenomics of atopic dermatitis

Case-control shotgun metagenomics of 138 stool samples from adults in Switzerland and Tanzania, comparing atopic dermatitis with healthy controls. machine-written summary

140 samples · 140 runs · CH, TZ · Adult · 2025 · 1.42 Gbp / sample

Sources
✓Sequence archive 972✓Abstract / description 140○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive972 sample values (collection date, country, health condition, health condition detail, latitude, location region, longitude)
✓ Abstract / description140 sample values (subject id)
○ Full textread; no usable statement or table · PMC13646880
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
2 sampling locations · 2 countries
Age
adult140
Condition
healthy_control71
other_disease68
allergy_or_atopy1
Country
CH75
TZ65
Body site
primary140
Collected 2022–2024
2022: 51 samples2023: 81 samples2024: 6 samples20222024
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 4 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 130 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 6 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.42 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category140 100%
country140 100%140
health_condition140 100%140
subject_id140 100%140
health_condition_detail140 100%140
collection_date138 99%138
detailed_location138 99%
latitude138 99%138
location_region138 99%138
longitude138 99%138
Papers (1)
  • Dietary Habits and Atopic Dermatitis Significantly Influence the Fecal Microbiome. 2026 PMID 42517538 own_data
Details
Archive description

Shotgun metagenomics of stool samples collected from adults in Tanzania and Switzerland with atopic dermatitis and healthy controls.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.description · “Shotgun metagenomics of stool samples collected from”
  • body site external_curation.infant_catalog · “body_site_call gut/stool”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • life stage study.description · “samples collected from adults in Tanzania and”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA120401712collection_date2022-05-27R10.90biosample.attribute:collection_date2022-05-27
SAMEA120401746collection_date2023-04-27R10.85biosample.attribute:collection datecollection date: 2023-04-27
SAMEA120401712countryTZR10.90sample.attr.geographic_location_country_and_or_seaTanzania
SAMEA120401712health_conditionother_diseaseR10.60biosample_attrCase
SAMEA120401746health_conditionhealthy_controlR10.85biosample.attribute:host disease statushost disease status: Control
SAMEA120401712health_condition_detailCaseR10.90sample.attr.host_disease_statusCase
SAMEA120401746health_condition_detailhealthy controlR10.85biosample.attribute:host disease statushost disease status: Control
SAMEA120401712latitude-3.3349R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude-3.334883 37.340381
SAMEA120401712location_regionKilimanjaroR10.60biosample.attribute:geographic_location_latitude+geographic_location_longitude-3.334883 37.340381
SAMEA120401712longitude37.3404R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude-3.334883 37.340381
SAMEA120401712subject_idSAMEA120401712R40.60design.one_sample_per_subject:abstracta total of 140 fecal samples from 69 AD patients and 71 HC from Tanzania (TZ) and Switzerland (CH) were analyzed
Sequencing

140 runs over 140 samples · mean 1.58 Gbp per run (median 1.42 Gbp, total 221.85 Gbp; 140 runs with a base count) · layout PAIRED 140 · platform ILLUMINA 140 · models Illumina NovaSeq X Plus (140) · 0% of runs with a Sandpiper profile · first public 2025-12-31

Authors (0)

No author record.

Downloads

PRJEB101120.csv.gz (4.9 KB) · parquet (77.3 KB) — all 140 samples, every field with route and confidence · PRJEB101120_determinations.csv.gz (8.1 KB) — 1,112 evidence rows

Samples (140 · every field this project has values for · hover a cell for its source)
Loading the sample table…