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PRJEB101484 ERP182887

Gut microbiota-immune compatibility for FMT in IBD (Italy)

Gut Microbiota - Lymphocyte Reaction (GMLR): a practical tool to optimize fecal microbiota transplantation (FMT) donor-recipient compatibility in IBD

10 fecal microbiome samples from adults with IBD in Italy, used to test an ex vivo donor-recipient immune compatibility assay (GMLR) to guide fecal microbiota transplantation donor selection. machine-written summary

10 samples · 10 runs · IT · Adult · 2026 · 2.35 Gbp / sample

Sources
✓Sequence archive 70○Abstract / description✓Full text 10○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive70 sample values (collection date, country, health condition, health condition detail, latitude, location region, longitude)
○ Abstract / descriptionread; no usable statement
✓ Full text10 sample values (location locality) · PMC13578986
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult10
Condition
ibd_unspecified10
Country
IT10
Body site
primary10
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 10 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 4.69 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category10 100%
country10 100%10
health_condition10 100%10
subject_id0 0%
collection_date10 100%10
detailed_location10 100%
health_condition_detail10 100%10
latitude10 100%10
location_locality10 100%10
location_region10 100%10
longitude10 100%10
Papers (1)
  • A functional immune-based platform for donor-recipient matching in faecal microbiota transplantation for inflammatory bowel disease. 2026 PMID 42705024 PMC13578986 own_data
Details
Archive description

Gut Microbiota - Lymphocyte Reaction (GMLR): a practical tool to optimize fecal microbiota transplantation (FMT) donor-recipient compatibility in IBD

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Gut Microbiota - Lymphocyte”
  • body site study.description · “Gut Microbiota - Lymphocyte”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA120421570collection_date2022-01-01R10.90biosample.attribute:collection_date2022-01-01
SAMEA120421570countryITR10.90sample.attr.geographic_location_country_and_or_seaItaly
SAMEA120421570health_conditionibd_unspecifiedR10.85biosample.attribute:descriptiondescription: Human gut metagenome of a patient with IBD
SAMEA120421570health_condition_detailHuman gut metagenome of a patient with IBDR10.85biosample.attribute:descriptiondescription: Human gut metagenome of a patient with IBD
SAMEA120421570latitude45.4643R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude45.46427 9.18951
SAMEA120421570location_localityMilanR30.70paper.fulltext.methodsOspedale Maggiore Policlinico (Milan, Italy)
SAMEA120421570location_regionLombardyR10.60biosample.attribute:geographic_location_latitude+geographic_location_longitude45.46427 9.18951
SAMEA120421570longitude9.1895R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude45.46427 9.18951
Sequencing

10 runs over 10 samples · mean 2.33 Gbp per run (median 2.35 Gbp, total 23.28 Gbp; 10 runs with a base count) · layout PAIRED 10 · platform ILLUMINA 10 · models Illumina NovaSeq 6000 (10) · 0% of runs with a Sandpiper profile · first public 2026-06-10

Authors (12)

Amoroso C first · Strati F · Maragno P · Caridi B · Noviello D · Gilodi M · Muià M · Frazzini S · Perillo F · Vecchi M · Caprioli F · Facciotti F last

Downloads

PRJEB101484.csv.gz (1.2 KB) · parquet (70.2 KB) — all 10 samples, every field with route and confidence · PRJEB101484_determinations.csv.gz (1.2 KB) — 80 evidence rows

Samples (10 · every field this project has values for · hover a cell for its source)
Loading the sample table…