Gut microbiome before/after Panchakarma therapy, India
10 gut metagenome samples from adults in India, studied for compositional and functional changes before and after Panchakarma (an Ayurvedic detoxification therapy), using an intervention design. machine-written summary
10 samples · 10 runs · IN · Adult · 2026 · 5.11 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 50 sample values (collection date, country, health condition, health condition detail, subject id) |
| – Abstract / description | no abstract or project description |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Other administered intervention (see intervention_detail) design single_arm_before_after · population healthy_control · Panchakarma Ayurvedic detoxification/rejuvenation therapy
“before and after Panchakarma therapy” — bioproject.description (study level; per-sample arms are in the intervention column below)
longitudinal — not resolved
5 of 5 people sampled more than once (10 samples; median 2, up to 2 per person).
Genera, mean relative abundance over 9 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 10 | 100% | ||||
| country | 10 | 100% | 10 | |||
| health_condition | 10 | 100% | 10 | |||
| subject_id | 10 | 100% | 10 | |||
| collection_date | 10 | 100% | 10 | |||
| health_condition_detail | 10 | 100% | 10 |
Archive description
The human gut microbiome plays a central role in maintaining digestive, metabolic, and immune health. Panchakarma, a classical Ayurvedic detoxification and rejuvenation therapy, is believed to restore internal balance and physiological harmony. However, its impact on the gut microbial ecosystem remains poorly understood. This study aims to investigate the compositional and functional changes in the gut microbiome before and after Panchakarma therapy using shotgun metagenomic sequencing.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “Mapping of the Gut Metagenome”
- body site study.description · “The human gut microbiome plays a”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA120472919 | collection_date | 2024 | R1 | 0.90 | biosample.attribute:collection_date | 2024 |
| SAMEA120472919 | country | IN | R1 | 0.90 | sample.attr.geographic_location_country_and_or_sea | India |
| SAMEA120472919 | health_condition | other_cancer | R1 | 0.85 | biosample.attribute:DESCRIPTION | Cancer_patient |
| SAMEA120472919 | health_condition_detail | Cancer_patient | R1 | 0.85 | biosample.attribute:DESCRIPTION | Cancer_patient |
| SAMEA120472919 | subject_id | 1 | R1 | 0.70 | sample.name_rule:sample_alias | 1_B |
Sequencing
10 runs over 10 samples · mean 5.29 Gbp per run (median 5.11 Gbp, total 52.93 Gbp; 10 runs with a base count) · layout PAIRED 10 · platform ILLUMINA 10 · models Illumina NovaSeq 6000 (10) · 90% of runs with a Sandpiper profile · first public 2026-01-11
Authors (0)
No author record.
Downloads
PRJEB102113.csv.gz (1.2 KB) · parquet (69.5 KB) — all 10 samples, every field with route and confidence · PRJEB102113_determinations.csv.gz (998 B) — 50 evidence rows