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PRJEB102130 ERP183531

FMT for CPE decolonization, longitudinal, South Korea

Shotgun metagenomics of FMT for CPE decolonization

132 fecal metagenome samples from adult patients in South Korea undergoing fecal microbiota transplantation (FMT) for CPE decolonization, collected longitudinally at baseline and weeks 1–5 post-FMT. machine-written summary

132 samples · 132 runs · KR · Adult · 2026 · 5.86 Gbp / sample

Sources
✓Sequence archive 528✓Abstract / description 264–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive528 sample values (collection date, country, health condition, health condition detail)
✓ Abstract / description264 sample values (intervention, intervention detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention · arms resolved

FMTFMT132 samples
single arm: samples on the intervention (no pre-intervention samples labelled)

Faecal microbiota transplantation design single_arm_before_after · population gi_infection_or_diarrhoea · FMT for CPE decolonization, baseline through week 5

“21 patients who underwent FMT for CPE decolonization” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 country
Age
adult132
Condition
gi_infection_or_diarrhoea132
Country
KR132
Body site
primary132
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 1 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 17 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 106 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 8 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 5.86 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolvedFMT donor → recipient — not resolved

Schedule stated by the source: “Baseline (pre-FMT) and weeks 1, 2, 3, 4, 5 after FMT; some patients lack samples at all timepoints due to censoring” (time origin: transplant); stated follow-up 35 d.

FMT for CPE decolonization: donor (D*) and recipient (F*) samples; donor-recipient link not published.

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category132 100%
country132 100%132
health_condition132 100%132
subject_id0 0%
collection_date132 100%132
health_condition_detail132 100%132
intervention132 100%132
intervention_detail132 100%132
Papers (1)
  • Fecal microbiota transplantation accelerates clearance of carbapenemase-producing Enterobacterales intestinal carriage: influence of recipient gut microbiome ecology. 2026 PMID 42583799 own_data
Details
Archive description

We performed shotgun metagenomic sequencing on longitudinal fecal samples collected from 21 patients who underwent FMT for CPE decolonization. Samples were obtained at baseline (pre-FMT) and at weeks 1, 2, 3, 4, and 5 after FMT. Patients were categorized into Success and Failure groups based on decolonization outcomes. Due to variations in clinical course and censoring, some patients did not have samples available at all time points.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.description · “sequencing on longitudinal fecal samples collected from”
  • body site external_curation.infant_catalog · “body_site_call gut”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA120614422collection_date2023R10.90biosample.attribute:collection_date2023
SAMEA120614422countryKRR10.90sample.attr.geographic_location_country_and_or_seaSouth Korea
SAMEA120614422health_conditiongi_infection_or_diarrhoeaR10.70sample.name_rule:descriptionD10_Failure_D
SAMEA120614422health_condition_detailD10_Failure_DR10.70sample.name_rule:descriptionD10_Failure_D
SAMEA120614422interventionfmtR40.50paper.abstractA longitudinal metagenomic subcohort of 21 FMT recipients (102 fecal samples) underwent shotgun sequencing
SAMEA120614422intervention_detailfecal microbiota transplantationR40.50paper.abstractWe evaluated fecal microbiota transplantation (FMT) for decolonization and response-associated recipient microbiome features.
Sequencing

132 runs over 132 samples · mean 5.86 Gbp per run (median 5.86 Gbp, total 773.25 Gbp; 132 runs with a base count) · layout PAIRED 132 · platform ILLUMINA 132 · models Illumina NovaSeq 6000 (132) · 0% of runs with a Sandpiper profile · first public 2026-03-31

Authors (0)

No author record.

Downloads

PRJEB102130.csv.gz (4.4 KB) · parquet (75.5 KB) — all 132 samples, every field with route and confidence · PRJEB102130_determinations.csv.gz (6.8 KB) — 792 evidence rows

Samples (132 · every field this project has values for · hover a cell for its source)
Loading the sample table…