Home › Studies › PRJEB104496
PRJEB104496 ERP185791

Gut microbiome in elderly adults, Spain, cross-sectional

The Ageing Imageomics Study

942 faecal samples from individuals aged 50 or older in Spain, analysed by shotgun metagenomics to study gut microbiota in relation to aging-associated factors, in a cross-sectional design. machine-written summary

942 samples · 942 runs · ES · Adult · 2026 · 2.53 Gbp / sample

Sources
✓Sequence archive 5,652○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive5,652 sample values (collection date, country, latitude, location region, longitude, subject id)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC13378717
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
elderly942
Country
ES942
Body site
primary942
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 2 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 1 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 5 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 670 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 261 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 3 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 2.53 Gbp per sample0130Gbp
Community composition
Alistipes 11.9%Prevotella 8.9%Bacteroides 7.3%Phocaeicola 4.8%Vescimonas 4.2%Faecalibacterium 3.9%Hominicoprocola 3.3%CAG-170 2.1%Fimenecus 1.9%UBA11524 1.7%CAG-177 1.6%Akkermansia 1.6%not assigned to a genus 7.9%other genera 38.8%

Genera, mean relative abundance over 930 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category942 100%
country942 100%942
health_condition0 0%
subject_id942 100%942
collection_date942 100%942
detailed_location942 100%
latitude942 100%942
location_region942 100%942
longitude942 100%942
Papers (1)
  • Ecological restructuring of the nonbacterial fecal microbiome in obesity across human cohorts. 2026 PMID 42458961 PMC13378717 unsure
Details
Archive description

Population observational study for the development of biomarkers of integral body image based on MRI in individuals 50 years of age or older and their relationship with factors in the biopsychosocial, cardiovascular, metabolomics, lipidomics, microbiomics, and other factors associated with aging. A total of 1015 subjects were recruited for cognitive tests and microbiota analysis. Faecal samples were collected from those subjects (n=942). For all samples, the metagenomic taxonomic and gene shot-gun analysis of the microbiota was carried out by a metagenomic approach, using a shotgun sequencing with the Illumina NextSeq with 150 bp x 2 chemistry.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.description · “and microbiota analysis. Faecal samples were collected”
  • body site external_curation.infant_catalog · “body_site_call gut”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA120812789collection_date2018R10.90biosample.attribute:collection_date2018
SAMEA120812789countryESR10.90sample.attr.geographic_location_country_and_or_seaSpain
SAMEA120812789latitude41.9831R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude41.98311 2.82493
SAMEA120812789location_regionCataloniaR10.60biosample.attribute:geographic_location_latitude+geographic_location_longitude41.98311 2.82493
SAMEA120812789longitude2.8249R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude41.98311 2.82493
SAMEA120812789subject_idAI_Sample1R10.70sample.name_rule:descriptionDNA metagenome from subject AI_Sample1
Sequencing

942 runs over 942 samples · mean 2.70 Gbp per run (median 2.53 Gbp, total 2,545.28 Gbp; 942 runs with a base count) · layout PAIRED 942 · platform ILLUMINA 942 · models NextSeq 2000 (942) · 99% of runs with a Sandpiper profile · first public 2026-02-10

Authors (10)

Gallardo-Nuell L first · Rosell-Díaz M · Garre-Olmo J · Puig J · Ramos R · Pons J · Pérez-Brocal V · Moya A · Mayneris-Perxachs J · Fernández-Real JM last

Downloads

PRJEB104496.csv.gz (23.6 KB) · parquet (107.7 KB) — all 942 samples, every field with route and confidence · PRJEB104496_determinations.csv.gz (38.3 KB) — 5,652 evidence rows

Samples (942 · every field this project has values for · hover a cell for its source)
Loading the sample table…