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PRJEB113070 ERP193496

Longitudinal gut metagenomics of CPE carriers in Singapore

Longitudinal metagenomics analysis of CPE carriers

432 paired short-read metagenomic samples from CPE (carbapenemase-producing Enterobacterales) carriers in Singapore, from the CaPES #2 project, collected in a longitudinal design across elderly (267) and adult (165) age categories. machine-written summary

432 samples · 432 runs · SG · Adult · 2026 · 4.02 Gbp / sample

Sources
✓Sequence archive 2,592○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive2,592 sample values (age, collection date, country, sex, subject id, timepoint)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
elderly267
adult165
Sex
female221
male211
Country
SG432
Body site
primary432
Collected 2021–2024
2021: 65 samples2022: 197 samples2023: 154 samples2024: 16 samples20212024
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 5 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 427 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 4.02 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

141 of 142 people sampled more than once (431 samples; median 3, up to 7 per person) · follow-up median 5 mo (max 11 mo) · median interval between samples 28 d (time from collection dates).

N0004N0004: day 0N0004: day 5N0004: day 14N0006N0006: day 0N0006: day 30N0006: day 155N0008N0008: day 0N0008: day 29N0008: day 42S0002S0002: day 0S0002: day 41S0002: day 81S0005S0005: day 0S0005: day 21S0005: day 37S0005: day 43S0007S0007: day 0S0007: day 15S0007: day 49S0009S0009: day 0S0009: day 9S0009: day 337S0010S0010: day 0S0010: day 10S0010: day 12S0014S0014: day 0S0014: day 63S0014: day 146S0021S0021: day 0S0021: day 22S0021: day 92S0024S0024: day 0S0024: day 71S0024: day 161S0027S0027: day 0S0027: day 5S0027: day 12S0027: day 21S0027: day 27S0027: day 34S0027: day 42S0028S0028: day 0S0028: day 12S0028: day 41S0029S0029: day 0S0029: day 12S0029: day 41S0030S0030: day 0S0030: day 25S0030: day 69T0001T0001: day 0T0001: day 13T0001: day 335T0002T0002: day 0T0002: day 167T0002: day 336T0005T0005: day 0T0005: day 16T0005: day 43T0007T0007: day 0T0007: day 7T0007: day 13T0012T0012: day 0T0012: day 18T0012: day 336T0013T0013: day 0T0013: day 13T0013: day 167T0014T0014: day 0T0014: day 27T0014: day 166T0014: day 333T0068T0068: day 0T0068: day 15T0068: day 36T0068: day 329T0069T0069: day 0T0069: day 11T0069: day 40T0069: day 83T0069: day 273T0074T0074: day 0T0074: day 9T0074: day 48T0074: day 330T0082T0082: day 0T0082: day 18T0082: day 39T0082: day 327T0086T0086: day 0T0086: day 13T0086: day 36T0086: day 345T0087T0087: day 0T0087: day 5T0087: day 46T0087: day 333T0088T0088: day 0T0088: day 14T0088: day 42T0088: day 329T0089T0089: day 0T0089: day 13T0089: day 41T0089: day 327T0094T0094: day 0T0094: day 12T0094: day 39T0094: day 173T0100T0100: day 0T0100: day 36T0100: day 78T0100: day 321T0102T0102: day 0T0102: day 14T0102: day 41T0102: day 83T0102: day 336T0111T0111: day 0T0111: day 11T0111: day 32T0111: day 44T0111: day 166T0147T0147: day 0T0147: day 13T0147: day 35T0147: day 331T0154T0154: day 0T0154: day 13T0154: day 41T0154: day 3350 d3 mo6 mo9 mo11 mo

Each row is one person (36 shown of 141); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category432 100%
country432 100%432
health_condition0 0%
subject_id432 100%432
age_at_collection_days432 100%432
collection_date432 100%432
sex432 100%432
timepoint_label432 100%432
Details
Archive description

This study repository includes all the 432 paired short-reads metagenomics samples from the CaPES #2 project (designed as "study" in the related paper).

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult and elderly by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site external_curation.infant_catalog · “body_site_call gut”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • life stage sample.attr.host_age · “68 (n=254/432)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA122692940age_at_collection_days7670.2R10.70sample.attr.host_age21
SAMEA122692940collection_date2023-05-02R10.90biosample.attribute:collection_date2023-05-02
SAMEA122692940countrySGR10.90sample.attr.geographic_location_country_and_or_seaSingapore
SAMEA122692940sexmaleR10.90sample.attr.host_sexMale
SAMEA122692940subject_idN0002R10.85sample.attr.subject_idN0002
SAMEA122692940timepoint_labelD0R10.85sample.attr.subject_visit_codeD0
Sequencing

432 runs over 432 samples · mean 4.03 Gbp per run (median 4.02 Gbp, total 1,739.45 Gbp; 432 runs with a base count) · layout PAIRED 432 · platform ILLUMINA 432 · models Illumina NovaSeq X (432) · 0% of runs with a Sandpiper profile · first public 2026-07-31

Authors (0)

No author record.

Downloads

PRJEB113070.csv.gz (14.5 KB) · parquet (88.8 KB) — all 432 samples, every field with route and confidence · PRJEB113070_determinations.csv.gz (19.8 KB) — 2,592 evidence rows

Samples (432 · every field this project has values for · hover a cell for its source)
Loading the sample table…