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PRJEB115009 ERP195227

Gut Microbiota in Alzheimer's: MIND Diet Intervention, USA

MICROBIOTA-Brain Axis in Alzheimers Disease: MIND Diet-Induced Effects

384 stool samples from Rush and Harvard cohorts in the USA, collected at Year 3 of a U19 study examining MIND diet-induced effects on the microbiota-brain axis in Alzheimer's disease; intervention design. machine-written summary

384 samples · 384 runs · US · Adult · 2026 · 2.18 Gbp / sample

Sources
✓Sequence archive 1,140–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive1,140 sample values (collection date, country, latitude, longitude)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

design single_arm_before_after · MIND diet intervention

Samples at a glance
1 sampling locations · 1 country
Age
adult384
Country
US328
Body site
primary384
Collected 2020–2021
2020: 95 samples2021: 61 samples20202021
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 55 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 9 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 12 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 37 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 143 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 128 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 2.18 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category384 100%
country328 85%328
health_condition0 0%
subject_id0 0%
latitude328 85%328
longitude328 85%328
collection_date156 41%156
Details
Archive description

Stool collection for the U19 occurred at Y3 (from both the Rush and Harvard cohorts).

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.description · “Stool collection for the”
  • body site external_curation.infant_catalog · “body_site_call gut”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA122901803collection_date2020-11-19R10.90biosample.attribute:collection_date2020-11-19
SAMEA122901803countryUSR10.90sample.attr.geographic_location_country_and_or_seaUSA
SAMEA122901803latitude35.9800R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude35.98 -78.9
SAMEA122901803longitude-78.9000R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude35.98 -78.9
Sequencing

384 runs over 384 samples · mean 2.05 Gbp per run (median 2.18 Gbp, total 788.65 Gbp; 384 runs with a base count) · layout PAIRED 384 · platform ILLUMINA 384 · models Illumina NovaSeq 6000 (384) · 0% of runs with a Sandpiper profile · first public 2026-06-30

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJEB115009.csv.gz (9.4 KB) · parquet (83.9 KB) — all 384 samples, every field with route and confidence · PRJEB115009_determinations.csv.gz (6.7 KB) — 1,140 evidence rows

Samples (384 · every field this project has values for · hover a cell for its source)
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