Gut metagenomes from ADRC participants, USA, longitudinal
1792 samples from participants in an Alzheimer's Disease Research Center cohort (USA), including cognitively normal controls, mild cognitive impairment, and Alzheimer's disease, followed longitudinally. machine-written summary
1,792 samples · 1,792 runs · US · Adult · 2026 · 0.89 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 4,222 sample values (collection date, country, latitude, longitude) |
| ✓ Abstract / description | 1,792 sample values (health condition detail) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal — not resolved
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 1,792 | 100% | ||||
| country | 744 | 42% | 744 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% | ||||
| health_condition_detail | 1,792 | 100% | 1,792 | |||
| latitude | 1,367 | 76% | 1,367 | |||
| longitude | 1,367 | 76% | 1,367 | |||
| collection_date | 744 | 42% | 744 |
Archive description
The AGMP ADRC Study is a targeted study that will recruit, assess, and longitudinally follow approximately 1000 participants already enrolled in an ADRC, for multiple years. Participants include cognitively normal “healthy controls” who may be at risk for Alzheimer’s disease, individuals with mild cognitive impairment (MCI), and individuals with Alzheimer’s Disease (AD). Most of these participants will have excellent characterization with neuropsychological testing, brain imaging, and a consensus-based confirmed diagnosis.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site external_curation.infant_catalog · “body_site_call gut”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA122903411 | collection_date | 2022-03-12 | R1 | 0.90 | biosample.attribute:collection_date | 2022-03-12 |
| SAMEA122903411 | country | US | R1 | 0.90 | sample.attr.geographic_location_country_and_or_sea | USA |
| SAMEA122902187 | health_condition_detail | mixed_case_control: cognitively normal healthy controls, mild cognitive impairment (MCI), and Alzheimer's Disease (AD) p | R4 | 0.50 | study.description | cognitively normal "healthy controls" |
| SAMEA122902187 | latitude | 35.9800 | R1 | 0.90 | biosample.attribute:geographic_location_latitude+geographic_location_longitude | 35.98 -78.9 |
| SAMEA122902187 | longitude | -78.9000 | R1 | 0.90 | biosample.attribute:geographic_location_latitude+geographic_location_longitude | 35.98 -78.9 |
Sequencing
1,792 runs over 1,792 samples · mean 1.41 Gbp per run (median 0.89 Gbp, total 2,529.99 Gbp; 1,792 runs with a base count) · layout PAIRED 1,792 · platform ILLUMINA 1,792 · models Illumina NovaSeq 6000 (1,792) · 0% of runs with a Sandpiper profile · first public 2026-06-30
Authors (0)
No author record.
Help complete this project
3 of the 4 core fields are below 50% coverage: country, health_condition, subject_id. Share metadata
Downloads
PRJEB115010.csv.gz (39.9 KB) · parquet (135.2 KB) — all 1,792 samples, every field with route and confidence · PRJEB115010_determinations.csv.gz (33.5 KB) — 6,014 evidence rows