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PRJEB38258 ERP121664

Gut microbiota in UK stoma patients after distal feeding

The long-term impact of distal feeding on patients with stoma

24 gut microbiome samples from adults in the United Kingdom with a stoma, studying the long-term impact of distal feeding after cancer therapy, using a cross-sectional design. machine-written summary

24 samples · 24 runs · GB · Adult · 2025 · 54.01 Gbp / sample

Sources
✓Sequence archive 192–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive192 sample values (collection date, country, health condition, health condition detail, latitude, location region, longitude, sex)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Controlled / prescribed diet or feeding regimen design observational_with_procedure · population colorectal_cancer · Distal feeding into defunctioned bowel after stoma surgery

“long-term impact of distal feeding” — study.title (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 sampling locations · 1 country
Age
adult24
Condition
colorectal_cancer17
healthy_control7
Sex
female13
male11
Country
GB24
Body site
primary24
Collected 2019–2020
2019: 18 samples2020: 6 samples20192020
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)this project, 30–100 Gbp: 24 samplesall projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 54.01 Gbp per sample0130Gbp
Community composition
Blautia_A 8.0%Bacteroides 7.9%Roseburia 6.3%Faecalibacterium 5.9%Ruminococcoides 5.4%Bifidobacterium 4.9%Mediterraneibacter 3.2%Anaerostipes 2.4%Gemmiger 2.3%Prevotella 2.0%Phocaeicola 2.0%Akkermansia 1.9%not assigned to a genus 2.3%other genera 45.6%

Genera, mean relative abundance over 18 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category24 100%
country24 100%24
health_condition24 100%24
subject_id0 0%
collection_date24 100%24
detailed_location24 100%
health_condition_detail24 100%24
latitude24 100%24
location_region24 100%24
longitude24 100%24
sex24 100%24
Papers (1)
  • Improving operative outcomes in patients with stomas 2026 own_data
Details
Archive description

To investigate differences in the gut microbiota after cancer therapy and stoma, and to investigate the impact of distal feeding on the gut microbiome in the longer term.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.62. Assay shotgun_dna.

  • host study.title · “patients with stoma”
  • body site study.description · “gut microbiota after cancer therapy”
  • life stage study.description · “gut microbiota after cancer therapy and stoma”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA6824532collection_date2019-10-29R10.90biosample.attribute:collection_date2019-10-29
SAMEA6824532countryGBR10.90sample.attr.geographic_location_country_and_or_seaUnited Kingdom
SAMEA6824532health_conditioncolorectal_cancerR10.70sample.name_rule:sample_descriptionTME patient and ileostomy reversed
SAMEA6824532health_condition_detailTME patient and ileostomy reversedR10.70sample.name_rule:sample_descriptionTME patient and ileostomy reversed
SAMEA6824532latitude51.5759R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude51.5759 -0.3202
SAMEA6824532location_regionEnglandR10.60biosample.attribute:geographic_location_latitude+geographic_location_longitude51.5759 -0.3202
SAMEA6824532longitude-0.3202R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude51.5759 -0.3202
SAMEA6824532sexfemaleR10.90sample.attr.host_sexfemale
Sequencing

24 runs over 24 samples · mean 54.33 Gbp per run (median 54.01 Gbp, total 1,303.80 Gbp; 24 runs with a base count) · layout PAIRED 24 · platform ILLUMINA 24 · models Illumina NovaSeq 6000 (24) · 75% of runs with a Sandpiper profile · first public 2025-05-18

Authors (0)

No author record.

Downloads

PRJEB38258.csv.gz (1.7 KB) · parquet (70.8 KB) — all 24 samples, every field with route and confidence · PRJEB38258_determinations.csv.gz (1.9 KB) — 192 evidence rows

Samples (24 · every field this project has values for · hover a cell for its source)
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