Healthy Danish gut microbiome controls for an MS study
N=149 fecal samples from healthy Danish adults used as controls in a case-control study examining gut microbiota alterations in multiple sclerosis patients via shotgun metagenomic sequencing. machine-written summary
150 samples · 272 runs · DK · Adult · 2022 · 2.55 Gbp / sample · cohort Alteration of Gut Microbiome in Patients With Schi
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 233 sample values (collection date, country) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC10140391, PMC9814178 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 150 | 100% | ||||
| country | 150 | 100% | 150 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% | ||||
| collection_date | 83 | 55% | 83 |
- The gut microbiota in multiple sclerosis varies with disease activity. 2023 PMID 36604748 PMC9814178 unsure
- Alteration of Gut Microbiome in Patients With Schizophrenia Indicates Links Between Bacterial Tyrosine Biosynthesis and Cognitive Dysfunction. 2023 PMID 37124355 PMC10140391 unsure
Archive description
Healthy danish metagenomic samples included in study "Alteration of gut microbiome in patients with schizophrenia indicates links between bacterial tyrosine biosynthesis and cognitive dysfunction" referenced under PRJEB41217 accession number.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.68. Assay shotgun_dna.
- host study.title · “Healthy danish metagenomic samples”
- body site run.scientific_name · “human gut metagenome”
- life stage study.description · “patients with schizophrenia indicates links”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA121025449 | collection_date | 2014 | R1 | 0.90 | biosample.attribute:collection_date | 2014 |
| SAMEA112189628 | country | DK | R1 | 0.90 | sample.attr.geographic_location_country_and_or_sea | Denmark |
Sequencing
272 runs over 150 samples · mean 1.50 Gbp per run (median 1.65 Gbp, total 408.89 Gbp; 272 runs with a base count) · layout SINGLE 272 · platform ION_TORRENT 272 · models Ion Torrent Proton (272) · 0% of runs with a Sandpiper profile · first public 2022-01-31 – 2026-01-22
Authors (33)
Thirion F first · Sellebjerg F · Fan Y · Lyu L · Hansen TH · Pons N · Levenez F · Quinquis B · Stankevic E · Søndergaard HB · Dantoft TM · Poulsen CS · Forslund SK · Vestergaard H · Hansen T · Brix S · Oturai A · Sørensen PS · Ehrlich SD · Pedersen O last · Speyer H · Nielsen T · Le Chatelier E · Fromentin S · Berland M · Plaza Oñate F · Galleron N · Markó L · Birkner T · Jørgensen T · Nordentoft M · Mors O · Benros ME
Help complete this project
2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata
Downloads
PRJEB41786.csv.gz (4.1 KB) · parquet (74.4 KB) — all 150 samples, every field with route and confidence · PRJEB41786_determinations.csv.gz (1.3 KB) — 233 evidence rows