Resistant dextrin fiber intervention, healthy women, France
100 fecal metagenome samples from healthy women in France, collected in an intervention trial comparing daily resistant dextrin (NUTRIOSE) supplementation to a control product over 6 weeks. machine-written summary
100 samples · 403 runs · FR · Adult · 2022 · 2.89 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 900 sample values (age, bmi, country, health condition, health condition detail, intervention, intervention detail, subject id) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 100 sample values (sex) · PMC9287035 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention · arms resolved
50 people have samples in more than one arm.
Prebiotic / dietary fibre supplement design randomized_controlled_trial · population healthy_control · NUTRIOSE resistant dextrin fiber supplement, 6 weeks, vs control
“supplemented daily with either RD” — abstract:35312171 (study level; per-sample arms are in the intervention column below)
longitudinal
50 of 50 people sampled more than once (100 samples; median 2, up to 2 per person) · follow-up median 42 d (max 42 d) · median interval between samples 42 d (time from timepoint labels). Schedule stated by the source: “stool at baseline and D42 (6 weeks of product consumption)” (time origin: intervention_start); stated follow-up 42 d.
Each row is one person (36 shown of 50); dots are samples at days since that person's first sample.
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 100 | 100% | ||||
| country | 100 | 100% | 100 | |||
| health_condition | 100 | 100% | 100 | |||
| subject_id | 100 | 100% | 100 | |||
| age_at_collection_days | 100 | 100% | 100 | |||
| bmi | 100 | 100% | 100 | |||
| health_condition_detail | 100 | 100% | 100 | |||
| intervention | 100 | 100% | 100 | |||
| intervention_detail | 100 | 100% | 100 | |||
| sex | 100 | 100% | 100 | |||
| timepoint_label | 100 | 100% | 100 |
- Diet Supplementation with NUTRIOSE, a Resistant Dextrin, Increases the Abundance of Parabacteroides distasonis in the Human Gut. 2022 PMID 35312171 PMC9287035 own_data
Archive description
This study aimed at confirming the impact of the resistant dextrin NUTRIOSE® (RD), a soluble fiber with demonstrated beneficial health effects, on the gut microbiota of healthy individuals.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “in the human gut”
- body site study.description · “effects, on the gut microbiota of healthy”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA110279520 | age_at_collection_days | 11688.0 | R1 | 0.85 | sample.attr.age | 32 |
| SAMEA110279520 | bmi | 18.91 | R1 | 0.90 | sample.attr.bmi | 18.91021071 |
| SAMEA110279520 | country | FR | R1 | 0.90 | sample.attr.geographic_location_country_and_or_sea | France |
| SAMEA110279520 | health_condition | healthy_control | R1 | 0.85 | biosample.attribute:product | product: RD |
| SAMEA110279520 | health_condition_detail | healthy individuals | R1 | 0.85 | biosample.attribute:product | product: RD |
| SAMEA110279520 | intervention | no_intervention | R1 | 0.90 | biosample.attribute:visit | visit: Baseline |
| SAMEA110279520 | intervention_detail | baseline before NUTRIOSE fibre supplementation | R1 | 0.90 | biosample.attribute:visit | visit: Baseline |
| SAMEA110279520 | sex | female | R3 | 0.70 | paper.fulltext.methods | female |
| SAMEA110279520 | subject_id | 1 | R1 | 0.85 | sample.attr.ind | 1 |
| SAMEA110279520 | timepoint_label | Baseline | R1 | 0.85 | sample.attr.visit | Baseline |
Sequencing
403 runs over 100 samples · mean 0.74 Gbp per run (median 0.72 Gbp, total 298.28 Gbp; 403 runs with a base count) · layout SINGLE 403 · platform ION_TORRENT 403 · models Ion Torrent Proton (403) · 0% of runs with a Sandpiper profile · first public 2022-07-07
Authors (15)
Thirion F first · Da Silva K · Plaza Oñate F · Alvarez AS · Thabuis C · Pons N · Berland M · Le Chatelier E · Galleron N · Levenez F · Vergara C · Chevallier H · Guérin-Deremaux L · Doré J · Ehrlich SD last
Downloads
PRJEB42906.csv.gz (4.0 KB) · parquet (75.5 KB) — all 100 samples, every field with route and confidence · PRJEB42906_determinations.csv.gz (8.3 KB) — 1,000 evidence rows