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PRJEB43044 ERP126963

Gut microbiome changes, COVID-19 vs travel, Hong Kong

Changes in human gut microbiome during the first wave of COVID-19 pandemic in comparison with pre-pandemic travel-related changes

Longitudinal study of 96 gut microbiome samples from Hong Kong, comparing changes during the first COVID-19 pandemic wave with pre-pandemic international travel-related changes in microbiome and resistome. machine-written summary

96 samples · 96 runs · HK · Age unknown · 2021 · 6.42 Gbp / sample

Sources
✓Sequence archive 672–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive672 sample values (collection date, country, latitude, location region, longitude, subject id, timepoint)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown96
Country
HK96
Body site
primary96
Collected 2018–2020
2018: 9 samples2019: 55 samples2020: 32 samples20182020
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 96 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.42 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

32 of 32 people sampled more than once (96 samples; median 3, up to 3 per person) · follow-up median 13 mo (max 17 mo) · median interval between samples 3 mo (time from collection dates). Schedule stated by the source: “Fecal sample before travel, after travel, and during the first wave of COVID-19 in Hong Kong” (time origin: other).

1010: day 010: day 1510: day 506102102: day 0102: day 21102: day 322106106: day 0106: day 9106: day 371119119: day 0119: day 13119: day 327120120: day 0120: day 19120: day 367122122: day 0122: day 23122: day 343124124: day 0124: day 36124: day 305128128: day 0128: day 14128: day 3571313: day 013: day 1313: day 481132132: day 0132: day 10132: day 273133133: day 0133: day 19133: day 347134134: day 0134: day 8134: day 340142142: day 0142: day 8142: day 170143143: day 0143: day 7143: day 1541717: day 017: day 1117: day 5081818: day 018: day 2118: day 4802929: day 029: day 529: day 47633: day 03: day 173: day 4973232: day 032: day 3032: day 5313636: day 036: day 1436: day 46444: day 04: day 154: day 5034444: day 044: day 1344: day 50555: day 05: day 165: day 4975151: day 051: day 1551: day 42066: day 06: day 276: day 5326262: day 062: day 1162: day 4077575: day 075: day 1575: day 2998888: day 088: day 1388: day 4188989: day 089: day 1389: day 4189090: day 090: day 1090: day 3759898: day 098: day 998: day 3219999: day 099: day 999: day 3210 d4 mo9 mo13 mo17 mo

Each row is one person (32 shown); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country96 100%96
health_condition0 0%
subject_id96 100%96
collection_date96 100%96
detailed_location96 100%
latitude96 100%96
location_region96 100%96
longitude96 100%96
timepoint_label96 100%96
Papers (1)
  • Gut microbiome and resistome changes during the first wave of the COVID-19 pandemic in comparison with pre-pandemic travel-related changes. 2021 PMID 33949663 PMC8135950 own_data
Details
Archive description

Using metagenomic sequencing, we comparatively examined the changes in gut microbiome and resistome following pre-pandemic international travels and during the first wave of COVID-19 pandemic.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.72. Assay shotgun_dna.

  • host study.title · “human gut microbiome during the first wave”
  • body site run.scientific_name · “gut metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA8023226collection_date2018-12-21R10.90biosample.attribute:collection_date2018-12-21
SAMEA8023226countryHKR10.90sample.attr.geographic_location_country_and_or_seaHong Kong
SAMEA8023226latitude22.3193R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude22.3193� N 114.1694� E
SAMEA8023226location_regionKowloon CityR10.60biosample.attribute:geographic_location_latitude+geographic_location_longitude22.3193� N 114.1694� E
SAMEA8023226longitude114.1694R10.90biosample.attribute:geographic_location_latitude+geographic_location_longitude22.3193� N 114.1694� E
SAMEA8023226subject_id13R10.70sample.name_rule:aliasTH13-BT
SAMEA8023226timepoint_labelFecal sample collected before travelR10.85biosample.attribute:descriptionFecal sample collected before travel
Sequencing

96 runs over 96 samples · mean 6.39 Gbp per run (median 6.42 Gbp, total 613.46 Gbp; 96 runs with a base count) · layout PAIRED 96 · platform DNBSEQ 96 · models DNBSEQ-G400 (96) · 0% of runs with a Sandpiper profile · first public 2021-08-30

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata

Downloads

PRJEB43044.csv.gz (3.7 KB) · parquet (74.5 KB) — all 96 samples, every field with route and confidence · PRJEB43044_determinations.csv.gz (6.1 KB) — 672 evidence rows

Samples (96 · every field this project has values for · hover a cell for its source)
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