Age and gut microbiome in adults, cross-sectional study
76 stool samples from adults, sequenced to study how age (under vs over 65 years) relates to intestinal microbiome composition; cross-sectional design. machine-written summary
76 samples · 76 runs · Adult · 2021 · 8.05 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ○ Sequence archive | records read; no usable sample values |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC8523055 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 68 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 76 | 100% | ||||
| country | 0 | 0% | ||||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% |
- The importance of age in compositional and functional profiling of the human intestinal microbiome. 2021 PMID 34662347 PMC8523055 unsure
Archive description
In this study the effect of demographic parameters on the intestinal microbiome was assessed. For this, stool samples from humans of different age were sequenced to quantify their specific intestinal microbial composition. Study subjects with an age under and over 65 years could be separeted through their intestinal microbiome using a random forest machine learning approach.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “and the human intestinal microbiome”
- body site study.description · “parameters on the intestinal microbiome was assessed.”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Sequencing
76 runs over 76 samples · mean 7.94 Gbp per run (median 8.05 Gbp, total 603.78 Gbp; 76 runs with a base count) · layout PAIRED 76 · platform ILLUMINA 76 · models Illumina HiSeq 3000 (57), Illumina NovaSeq 6000 (19) · 89% of runs with a Sandpiper profile · first public 2021-06-10
Authors (6)
Herzog EL first · Wäfler M · Keller I · Wolf S · Zinkernagel MS · Zysset-Burri DC last
Help complete this project
3 of the 4 core fields are below 50% coverage: country, health_condition, subject_id. Share metadata
Downloads
PRJEB44233.csv.gz (2.5 KB) · parquet (71.2 KB) — all 76 samples, every field with route and confidence · PRJEB44233_determinations.csv.gz (168 B) — 0 evidence rows