Gut microbiome of recreational runners, longitudinal
240 faecal metagenome samples from healthy adult recreational (non-elite) runners (n=62), collected at 4 time points over 7 weeks, examined for links to fitness level and training load; longitudinal design. machine-written summary
240 samples · 240 runs · IE · Adult · 2023 · 1.25 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ○ Sequence archive | records read; no usable sample values |
| ✓ Abstract / description | 240 sample values (lifestyle detail) |
| ✓ Full text | 480 sample values (location locality, location site) · PMC11684919, PMC11829997 |
| ✓ Supplementary tables | 1,200 sample values (age, bmi, sex, subject id, timepoint) |
| ✓ External resources | 720 sample values (country, health condition, health condition detail) · from GMrepo v3 |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
design observational_with_procedure
longitudinal — not resolved
62 of 62 people sampled more than once (240 samples; median 4, up to 4 per person). Schedule stated by the source: “4 stool samples per participant over a 7-week period”; stated follow-up 49 d.
Genera, mean relative abundance over 214 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 240 | 100% | ||||
| country | 240 | 100% | 240 | |||
| health_condition | 240 | 100% | 240 | |||
| subject_id | 240 | 100% | 240 | |||
| age_at_collection_days | 240 | 100% | 240 | |||
| bmi | 240 | 100% | 240 | |||
| detailed_location | 240 | 100% | ||||
| health_condition_detail | 240 | 100% | 240 | |||
| lifestyle_detail | 240 | 100% | 240 | |||
| location_locality | 240 | 100% | 240 | |||
| location_site | 240 | 100% | 240 | |||
| sex | 240 | 100% | 240 | |||
| timepoint_label | 240 | 100% | 240 |
- Temporal stability and lack of variance in microbiome composition and functionality in fit recreational athletes. 2025 PMID 39955324 PMC11829997 own_data
- Cataloging metagenome-assembled genomes and microbial genes from the athlete gut microbiome. 2024 PMID 39741946 PMC11684919 unsure
Archive description
The gut microbiomes of recreational athletes reflect differences in fitness levels and training load
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.57. Assay shotgun_dna.
- host run.scientific_name · “human gut metagenome”
- body site run.scientific_name · “human gut metagenome”
- life stage study.title · “recreational athletes reflect differences”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA8985339 | age_at_collection_days | 13514.0 | R2 | 0.80 | paper.supp.41598_2025_88723_MOESM1_ESM.xlsx[Supp_T.2!Age] | 37 |
| SAMEA8985339 | bmi | 24.75 | R2 | 0.80 | paper.supp.41598_2025_88723_MOESM1_ESM.xlsx[Supp_T.2!BMI] | 24.7531 |
| SAMEA8985339 | country | IE | R2 | 0.75 | external.gmrepo source | country: Ireland |
| SAMEA8985339 | health_condition | healthy_control | R2 | 0.75 | external.gmrepo source | phenotype: Health |
| SAMEA8985339 | health_condition_detail | Health | R2 | 0.75 | external.gmrepo source | phenotype: Health |
| SAMEA8985339 | lifestyle_detail | recreational (non-elite) runners | R4 | 0.45 | paper.abstract | recreational (non-elite) runners (n = 62) with serial |
| SAMEA8985339 | location_locality | Cork | R3 | 0.70 | paper.fulltext.methods | Cork Teaching Hospitals, Cork, Ireland |
| SAMEA8985339 | location_site | Cork Teaching Hospitals | R3 | 0.70 | paper.fulltext.methods | Cork Teaching Hospitals, Cork, Ireland |
| SAMEA8985339 | sex | male | R2 | 0.80 | paper.supp.41598_2025_88723_MOESM1_ESM.xlsx[Supp_T.2!Sex] | Male |
| SAMEA8985339 | subject_id | Participant 1004 | R2 | 0.80 | paper.supp.41598_2025_88723_MOESM1_ESM.xlsx[Supp_T.2!Participant] | Participant 1004 |
| SAMEA8985339 | timepoint_label | Visit 2 | R2 | 0.80 | paper.supp.41598_2025_88723_MOESM1_ESM.xlsx[Supp_T.2!Visit] | Visit 2 |
Sequencing
240 runs over 240 samples · mean 1.31 Gbp per run (median 1.25 Gbp, total 314.96 Gbp; 240 runs with a base count) · layout PAIRED 240 · platform ILLUMINA 240 · models NextSeq 500 (240) · 89% of runs with a Sandpiper profile · first public 2023-01-26 – 2023-01-28
Authors (12)
Wosinska L first · Walsh LH · Walsh CJ · Cotter PD · Guinane CM · O'Sullivan O last · O' Donovan CM first · Nori SRC · Shanahan F · Celentano G · Murphy TB · Sullivan OO last
Downloads
PRJEB46398.csv.gz (7.2 KB) · parquet (79.9 KB) — all 240 samples, every field with route and confidence · PRJEB46398_determinations.csv.gz (15.0 KB) — 2,640 evidence rows