Gut microbiota in multiple sclerosis, Denmark, case-control
Shotgun fecal metagenomes from 148 Danish multiple sclerosis cases and 148 matched healthy controls, a case-control study linking gut bacterial and viral microbiota to disease activity and blood biomarkers. machine-written summary
148 samples · 625 runs · DK · Adult · 2022 · 2.96 Gbp / sample · cohort Alteration of Gut Microbiome in Patients With Schi
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 148 sample values (country) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 444 sample values (collection date, location locality, location site) · PMC9814178 |
| ✓ Supplementary tables | 148 sample values (subject id) |
| ✓ External resources | 296 sample values (health condition, health condition detail) · from GMrepo v3 |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 148 | 100% | ||||
| country | 148 | 100% | 148 | |||
| health_condition | 148 | 100% | 148 | |||
| subject_id | 148 | 100% | 148 | |||
| collection_date | 148 | 100% | 148 | |||
| detailed_location | 148 | 100% | ||||
| health_condition_detail | 148 | 100% | 148 | |||
| location_locality | 148 | 100% | 148 | |||
| location_site | 148 | 100% | 148 |
- The gut microbiota in multiple sclerosis varies with disease activity. 2023 PMID 36604748 PMC9814178 own_data
Archive description
The gut microbiota in multiple sclerosis varies with disease activity
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “The gut microbiota in multiple”
- body site study.description · “The gut microbiota in multiple”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA112189709 | collection_date | 2013-04/2014-06 | R3 | 0.70 | paper.fulltext.methods | in the period April 2013 to June 2014 |
| SAMEA112189709 | country | DK | R1 | 0.90 | sample.attr.geographic_location_country_and_or_sea | Denmark |
| SAMEA112189709 | health_condition | neurological_psychiatric | R2 | 0.75 | external.gmrepo source | phenotype: Multiple Sclerosis |
| SAMEA112189709 | health_condition_detail | Multiple Sclerosis | R2 | 0.75 | external.gmrepo source | phenotype: Multiple Sclerosis |
| SAMEA112189709 | location_locality | Copenhagen | R3 | 0.70 | paper.fulltext.methods | Rigshospitalet University Hospital, Copenhagen |
| SAMEA112189709 | location_site | Danish Multiple Sclerosis Center, Rigshospitalet University Hospital | R3 | 0.70 | paper.fulltext.methods | Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet University Hospital |
| SAMEA112189709 | subject_id | MS_1 | R2 | 0.80 | paper.supp.13073_2022_1148_MOESM1_ESM.xlsx[Table S2!col0] | MS_1 |
Sequencing
625 runs over 148 samples · mean 0.71 Gbp per run (median 0.44 Gbp, total 441.56 Gbp; 625 runs with a base count) · layout SINGLE 625 · platform ION_TORRENT 625 · models Ion Torrent Proton (625) · 0% of runs with a Sandpiper profile · first public 2022-12-04
Authors (20)
Thirion F first · Sellebjerg F · Fan Y · Lyu L · Hansen TH · Pons N · Levenez F · Quinquis B · Stankevic E · Søndergaard HB · Dantoft TM · Poulsen CS · Forslund SK · Vestergaard H · Hansen T · Brix S · Oturai A · Sørensen PS · Ehrlich SD · Pedersen O last
Downloads
PRJEB51635.csv.gz (5.0 KB) · parquet (76.7 KB) — all 148 samples, every field with route and confidence · PRJEB51635_determinations.csv.gz (7.7 KB) — 1,036 evidence rows