Gut microbiota follow-up in T2D diet intervention
95 gut microbiome samples from adults with type 2 diabetes, randomized to WTP diet or usual care for 3 months, with a one-year follow-up examining gut microbiota, diet, and host phenotype relationships. machine-written summary
95 samples · 95 runs · Adult · 2024 · 10.44 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 285 sample values (intervention, subject id, timepoint) |
| ✓ Abstract / description | 190 sample values (health condition, health condition detail) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention · arms resolved
design randomized_controlled_trial
longitudinal — not resolved
Genera, mean relative abundance over 91 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 95 | 100% | ||||
| country | 0 | 0% | ||||
| health_condition | 95 | 100% | 95 | |||
| subject_id | 95 | 100% | 95 | |||
| health_condition_detail | 95 | 100% | 95 | |||
| intervention | 95 | 100% | 95 | |||
| timepoint_label | 95 | 100% | 95 |
Archive description
T2D patients were randomly divided into two groups receiving WTP diet or usual care for 3 month. The gut microbiota changed and the host clinical parameters were improved. A one-year follow-up was conducted for both groups to further explore the relationships between gut microbiota, diet and host phenotype.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “Follow up of gut microbitoa targeted interventioon”
- body site study.description · “3 month. The gut microbiota changed and”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA14370038 | health_condition | type2_diabetes | R4 | 0.50 | study.description | T2D patients were randomly divided into two groups |
| SAMEA14370038 | health_condition_detail | Type 2 diabetes | R4 | 0.50 | study.description | T2D patients |
| SAMEA14370038 | intervention | no_intervention | R1 | 0.70 | sample.name_rule:alias | 3U001 |
| SAMEA14370038 | subject_id | U001 | R1 | 0.85 | biosample.attribute:DESCRIPTION | follow-up sample of U001 |
| SAMEA14370038 | timepoint_label | follow-up | R1 | 0.70 | sample.name_rule:description | follow-up sample of U001 |
Sequencing
95 runs over 95 samples · mean 10.49 Gbp per run (median 10.44 Gbp, total 996.33 Gbp; 95 runs with a base count) · layout PAIRED 95 · platform ILLUMINA 95 · models Illumina HiSeq 3000 (95) · 96% of runs with a Sandpiper profile · first public 2024-05-08
Authors (0)
No author record.
Downloads
PRJEB52732.csv.gz (3.3 KB) · parquet (73.3 KB) — all 95 samples, every field with route and confidence · PRJEB52732_determinations.csv.gz (4.4 KB) — 475 evidence rows