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PRJEB75460 ERP160037

Heart failure phenotyping by echocardiography, USA

PREDICT 2

975 samples from adults in the USA. Cross-sectional study of transthoracic echocardiography findings in heart failure, focusing on dilated cardiomyopathy diagnosis and ventricular function assessment. machine-written summary

975 samples · 975 runs · US · Adult · 2024 · 7.73 Gbp / sample · cohort Gut micro-organisms associated with health, nutrit

Sources
✓Sequence archive 1,950○Abstract / description✓Full text 975○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive1,950 sample values (collection date, country)
○ Abstract / descriptionread; no usable statement
✓ Full text975 sample values (subject id) · PMC5574280
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
adult975
Country
US975
Body site
primary975
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 1 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 4 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 49 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 580 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 339 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)this project, 30–100 Gbp: 2 samplesall projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.73 Gbp per sample0130Gbp
Community composition
Bacteroides 10.2%Phocaeicola 8.1%Faecalibacterium 6.8%Blautia_A 6.6%Alistipes 5.1%Prevotella 4.2%Roseburia 3.1%Fusicatenibacter 2.3%Gemmiger 1.6%Ruminococcoides 1.6%Lachnospira 1.6%Parabacteroides 1.4%not assigned to a genus 4.4%other genera 43.0%

Genera, mean relative abundance over 895 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category975 100%
country975 100%975
health_condition0 0%
subject_id975 100%975
collection_date975 100%975
Papers (4)
  • Diagnosis and assessment of dilated cardiomyopathy: a guideline protocol from the British Society of Echocardiography. 2017 PMID 28592613 PMC5574280 own_data
  • Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts. 2024 PMID 39558133 PMC11602726 unsure
  • Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals. 2025 PMID 39762435 PMC11726441 unsure
  • Gut micro-organisms associated with health, nutrition and dietary interventions. 2026 PMID 41372407 PMC12893911 unsure
Details
Archive description

PREDICT 2

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site external_curation.infant_catalog · “body_site_call gut”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA115665881collection_date2019R10.90biosample.attribute:collection_date2019
SAMEA115665881countryUSR10.90sample.attr.geographic_location_country_and_or_seaUSA
SAMEA115665881subject_idSAMEA115665881R30.70design.one_sample_per_subject:fulltextPREDICT 2 study ( NCT03983733 ) had a similar collection protocol to PREDICT 1 but was conducted entirely remotely and included data from 975 people
Sequencing

975 runs over 975 samples · mean 8.83 Gbp per run (median 7.73 Gbp, total 8,604.64 Gbp; 975 runs with a base count) · layout PAIRED 975 · platform ILLUMINA 975 · models unspecified (975) · 92% of runs with a Sandpiper profile · first public 2024-06-13 – 2024-06-17

Authors (62)

Mathew T first · Williams L · Navaratnam G · Rana B · Wheeler R · Collins K · Harkness A · Jones R · Knight D · O'Gallagher K · Oxborough D · Ring L · Sandoval J · Stout M · Sharma V · Steeds RP · British Society of Echocardiography Education Committee last · Manghi P first · Bhosle A · Wang K · Marconi R · Selma-Royo M · Ricci L · Asnicar F · Golzato D · Ma W · Hang D · Thompson KN · Franzosa EA · Nabinejad A · Tamburini S · Rimm EB · Garrett WS · Sun Q · Chan AT · Valles-Colomer M · Arumugam M · Bermingham KM · Giordano F · Davies R · Hadjigeorgiou G · Wolf J · Strowig T · Berry SE · Huttenhower C · Spector TD · Segata N · Song M last · Fackelmann G first · Carlino N · Heidrich V · Piccinno G · Piperni E · Arrè A · Bakker E · Creedon AC · Francis L · Capdevila Pujol J · Baldanzi G · Mladenovic K · Amati F · Ganesh S

Downloads

PRJEB75460.csv.gz (24.4 KB) · parquet (109.7 KB) — all 975 samples, every field with route and confidence · PRJEB75460_determinations.csv.gz (16.8 KB) — 2,925 evidence rows

Samples (975 · every field this project has values for · hover a cell for its source)
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