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PRJEB75463 ERP160040

PREDICT 3 US22A: gut microbiome, US adults, cross-sectional

PREDICT 3 US22A

Cross-sectional cohort of 8,468 gut microbiome samples from adults in the USA, part of a multinational study (PREDICT 3) examining diet-pattern (omnivore, vegetarian, vegan) signatures in the gut microbiome. machine-written summary

8,469 samples · 8,469 runs · US · Adult · 2024 · 4.72 Gbp / sample · cohort Gut micro-organisms associated with health, nutrit

Sources
✓Sequence archive 16,938○Abstract / description✓Full text 8,469○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive16,938 sample values (collection date, country)
○ Abstract / descriptionread; no usable statement
✓ Full text8,469 sample values (subject id) · PMC11602726, PMC11726441, PMC12893911
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
adult8,469
Country
US8,469
Body site
primary8,469
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 339 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 8,052 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 78 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 4.72 Gbp per sample0130Gbp
Community composition
Blautia_A 7.8%Bacteroides 7.2%Faecalibacterium 7.0%Roseburia 5.5%Phocaeicola 5.1%Alistipes 3.5%Ruminococcoides 3.0%Prevotella 2.8%Gemmiger 2.3%Fusicatenibacter 2.2%Mediterraneibacter 2.1%Bifidobacterium 2.0%not assigned to a genus 6.8%other genera 42.6%

Genera, mean relative abundance over 7,619 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category8,469 100%
country8,469 100%8,469
health_condition0 0%
subject_id8,469 100%8,469
collection_date8,469 100%8,469
Papers (3)
  • Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts. 2024 PMID 39558133 PMC11602726 unsure
  • Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals. 2025 PMID 39762435 PMC11726441 unsure
  • Gut micro-organisms associated with health, nutrition and dietary interventions. 2026 PMID 41372407 PMC12893911 unsure
Details
Archive description

PREDICT 3 US22A

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site external_curation.infant_catalog · “body_site_call gut”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA117311710collection_date2022R10.90biosample.attribute:collection_date2022
SAMEA117311710countryUSR10.90sample.attr.geographic_location_country_and_or_seaUSA
SAMEA117311710subject_idSAMEA117311710R30.70design.one_sample_per_subject:fulltextn = 8,470 participants from the USA aged 18–90 years
Sequencing

8,469 runs over 8,469 samples · mean 4.93 Gbp per run (median 4.72 Gbp, total 41,763.39 Gbp; 8,469 runs with a base count) · layout PAIRED 8,469 · platform ILLUMINA 8,469 · models unspecified (8,469) · 90% of runs with a Sandpiper profile · first public 2024-11-21 – 2024-11-23

Authors (45)

Manghi P first · Bhosle A · Wang K · Marconi R · Selma-Royo M · Ricci L · Asnicar F · Golzato D · Ma W · Hang D · Thompson KN · Franzosa EA · Nabinejad A · Tamburini S · Rimm EB · Garrett WS · Sun Q · Chan AT · Valles-Colomer M · Arumugam M · Bermingham KM · Giordano F · Davies R · Hadjigeorgiou G · Wolf J · Strowig T · Berry SE · Huttenhower C · Spector TD · Segata N · Song M last · Fackelmann G first · Carlino N · Heidrich V · Piccinno G · Piperni E · Arrè A · Bakker E · Creedon AC · Francis L · Capdevila Pujol J · Baldanzi G · Mladenovic K · Amati F · Ganesh S

Downloads

PRJEB75463.csv.gz (201.4 KB) · parquet (435.7 KB) — all 8,469 samples, every field with route and confidence · PRJEB75463_determinations.csv.gz (140.3 KB) — 25,407 evidence rows

Samples (8,469 · every field this project has values for · hover a cell for its source)
Loading the sample table…