Gut microbiome of healthy controls in GALAXY study, Denmark
131 gut metagenome samples from healthy adult controls recruited at Odense University Hospital, Denmark, matched by gender, age and partial BMI to alcohol-related liver disease patients; case-control design. machine-written summary
131 samples · 391 runs · DK · Adult · 2024 · 7.73 Gbp / sample · cohort Alcohol-related liver disease disrupts bile acid h
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 131 sample values (country) |
| ✓ Abstract / description | 655 sample values (collection date, health condition, health condition detail, location locality, location site) |
| ○ Full text | read; no usable statement or table · PMC13233754 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 131 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 131 | 100% | 131 | |||
| health_condition | 131 | 100% | 131 | |||
| subject_id | 0 | 0% | ||||
| collection_date | 131 | 100% | 131 | |||
| detailed_location | 131 | 100% | ||||
| health_condition_detail | 131 | 100% | 131 | |||
| location_locality | 131 | 100% | 131 | |||
| location_site | 131 | 100% | 131 |
- Alcohol-related liver disease disrupts bile acid homeostasis and gut microbial bile acid metabolism. 2026 PMID 41935631 PMC13233754 unsure
Archive description
This study involved healthy participants recruited between 2016 and 2018 at Odense University Hospital. The inclusion criteria specified individuals aged 18-75 who were matched by gender, age and (partially) BMI to alcohol-related liver disease patients from the GALA-ALD cohort.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult and elderly by opus_adjudicated with confidence 0.60. Assay shotgun_dna.
- host study.description · “healthy participants recruited between 2016 and 2018”
- body site study.title · “gut microbiome of healthy participants”
- life stage study.description · “individuals aged 18-75”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA115779873 | collection_date | 2016/2018 | R4 | 0.45 | ena.study_description | recruited between 2016 and 2018 at Odense |
| SAMEA115779873 | country | DK | R1 | 0.90 | sample.attr.geographic_location_country_and_or_sea | Denmark |
| SAMEA115779873 | health_condition | healthy_control | R4 | 0.50 | study.description | healthy participants recruited |
| SAMEA115779873 | health_condition_detail | Healthy controls | R4 | 0.50 | study.description | healthy participants recruited |
| SAMEA115779873 | location_locality | Odense | R4 | 0.45 | ena.study_description | at Odense University Hospital |
| SAMEA115779873 | location_site | Odense University Hospital | R4 | 0.45 | ena.study_description | recruited between 2016 and 2018 at Odense University Hospital |
Sequencing
391 runs over 131 samples · mean 2.62 Gbp per run (median 2.81 Gbp, total 1,024.14 Gbp; 391 runs with a base count) · layout PAIRED 261, SINGLE 130 · platform ILLUMINA 391 · models Illumina HiSeq 4000 (260), Illumina NovaSeq 6000 (82), NextSeq 500 (49) · 93% of runs with a Sandpiper profile · first public 2024-11-12 – 2025-04-14
Authors (25)
Keller MI first · de Zawadzki A · Thiele M · Suvitaival T · Sulek K · Kuhn M · Schudoma C · Podlesny D · Nishijima S · Fullam A · Kim CY · Niu L · Wretlind A · Hansen JK · Israelsen M · Johansen S · Akanni W · Hazenbrink D · Juel HB · Mann M · Hansen T · Krag A · Bork P · Legido-Quigley C · GALAXY & MicrobLiver consortia last
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata
Downloads
PRJEB76664.csv.gz (4.0 KB) · parquet (74.7 KB) — all 131 samples, every field with route and confidence · PRJEB76664_determinations.csv.gz (3.4 KB) — 786 evidence rows