Gut microbiome in major depressive disorder, Spain
Case-control study of 119 stool samples from adults in Spain, comparing gut microbiome profiles between subjects with major depressive disorder and non-depressed controls using shotgun metagenomics. machine-written summary
119 samples · 119 runs · ES · Age unknown · 2024 · 20.61 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 474 sample values (country, health condition, health condition detail, sex) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 238 sample values (collection date, subject id) · PMC13011431 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 119 | 100% | ||||
| country | 119 | 100% | 119 | |||
| health_condition | 119 | 100% | 119 | |||
| subject_id | 119 | 100% | 119 | |||
| collection_date | 119 | 100% | 119 | |||
| health_condition_detail | 119 | 100% | 119 | |||
| sex | 117 | 98% | 117 |
- Gut microbiome signatures associated with depression and obesity. 2026 PMID 41615149 PMC13011431 own_data
Archive description
We performed a cross-sectional study with a total of 105 subjects, 43 with major depression disorder and 62 non-depressed controls. We analyzed the microbiome in stool samples by shotgun metagenomics and recorded clinical, anthropometric, and lifestyle data.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.73. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.description · “microbiome in stool samples by shotgun metagenomics”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMEA115782307 | collection_date | 2017-09/2020-10 | R3 | 0.70 | paper.fulltext.methods | recruited 119 participants from September 2017 to October 2020 |
| SAMEA115782307 | country | ES | R1 | 0.90 | sample.attr.geographic_location_country_and_or_sea | Spain |
| SAMEA115782307 | health_condition | healthy_control | R1 | 0.85 | biosample.attribute:description | Control |
| SAMEA115782307 | health_condition_detail | Control | R1 | 0.85 | biosample.attribute:description | Control |
| SAMEA115782307 | sex | male | R1 | 0.90 | sample.attr.sex | hombre |
| SAMEA115782307 | subject_id | SAMEA115782307 | R3 | 0.75 | design.one_sample_per_subject:fulltext | We recruited 119 participants from September 2017 to October 2020. ... the cross-sectional design of |
Sequencing
119 runs over 119 samples · mean 19.37 Gbp per run (median 20.61 Gbp, total 2,305.55 Gbp; 119 runs with a base count) · layout PAIRED 119 · platform DNBSEQ 119 · models DNBSEQ-T7 (119) · 0% of runs with a Sandpiper profile · first public 2024-07-05
Authors (16)
Mora-Martínez C first · Molina-Mendoza G · Cenit MC · Medina-Rodríguez EM · Larroya-García A · Sanchez-Carro Y · Gonzalez-Blanco L · Bobes J · Lopez-Garcia P · Zandio-Zorrilla M · Lahortiga-Ramos F · Gili M · Garcia-Toro M · Barcelo B · Ibarra O · Sanz Y last
Downloads
PRJEB76994.csv.gz (4.0 KB) · parquet (74.9 KB) — all 119 samples, every field with route and confidence · PRJEB76994_determinations.csv.gz (4.7 KB) — 712 evidence rows