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PRJEB77202 ERP161679

Cork Nutrition Cohort for Infants, Ireland

Cork Nutrition Cohort

538 gut metagenome samples from the Cork Nutrition Cohort for Infants, Ireland. No condition, intervention, or study design details are specified in the available sources. machine-written summary

538 samples · 539 runs · IE · Infant / toddler · 2025 · 2.32 Gbp / sample · cohort Early life microbial succession in the gut follows

One study deposited as 2 BioProjects (646 catalog samples together): PRJEB77202 · PRJNA1413407 · show together

Sources
✓Sequence archive 2,152✓Abstract / description 538○Full text✓Supplementary tables 352–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive2,152 sample values (collection date, country, subject id, timepoint)
✓ Abstract / description538 sample values (location locality)
○ Full textread; no usable statement or table · PMC11733223
✓ Supplementary tables352 sample values (age)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
infant352
unknown186
Country
IE538
Body site
primary538
Collected 2015–2017
2015: 2 samples2016: 321 samples2017: 215 samples20152017
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 1 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 1 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 46 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 322 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 164 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 4 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 2.32 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

162 of 164 people sampled more than once (536 samples; median 3, up to 7 per person) · follow-up median 7 mo (max 14 mo) · median interval between samples 3 mo (time from collection dates).

100100: day 0100: day 31100: day 150100: day 245102102: day 0102: day 35102: day 92102: day 246108108: day 0108: day 29108: day 246108: day 344112112: day 0112: day 64112: day 223112: day 310113113: day 0113: day 65113: day 122113: day 217113: day 304114114: day 0114: day 28114: day 87114: day 147114: day 244114: day 342122122: day 0122: day 24122: day 90122: day 153122: day 335126126: day 0126: day 89126: day 245126: day 343129129: day 0129: day 28129: day 150129: day 243129: day 343131131: day 0131: day 127131: day 212131: day 302138138: day 0138: day 32138: day 84138: day 150138: day 335141141: day 0141: day 58141: day 120141: day 218141: day 302144144: day 0144: day 33144: day 90144: day 245145145: day 0145: day 62145: day 215145: day 302160160: day 0160: day 60160: day 122160: day 217164164: day 0164: day 32164: day 90164: day 150164: day 249168168: day 0168: day 29168: day 90168: day 246175175: day 0175: day 59175: day 157175: day 245176176: day 0176: day 30176: day 88176: day 151176: day 242177177: day 0177: day 27177: day 84177: day 144177: day 2421818: day 018: day 3018: day 9418: day 15518: day 343180180: day 0180: day 34180: day 89180: day 250186186: day 0186: day 55186: day 123186: day 2141919: day 019: day 3319: day 9219: day 25119: day 335199199: day 0199: day 31199: day 88199: day 151199: day 242216216: day 0216: day 33216: day 88216: day 252216: day 339238238: day 0238: day 29238: day 91238: day 150238: day 247238: day 3362525: day 025: day 2925: day 5925: day 12125: day 17625: day 27525: day 3603333: day 033: day 2833: day 14833: day 24633: day 3353636: day 036: day 3236: day 15336: day 24536: day 3403737: day 037: day 2837: day 8737: day 14737: day 2484646: day 046: day 6346: day 12046: day 21746: day 3084848: day 048: day 2848: day 9148: day 15748: day 3296565: day 065: day 2865: day 8865: day 24565: day 3359494: day 094: day 2994: day 8894: day 14494: day 25694: day 3269999: day 099: day 3199: day 8499: day 15399: day 3280 d3 mo6 mo9 mo12 mo

Each row is one person (36 shown of 162); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition
Bifidobacterium 46.3%Escherichia 7.2%Veillonella 4.3%Bacteroides 4.0%Streptococcus 3.5%Phocaeicola 3.3%Mediterraneibacter 3.2%Klebsiella 2.5%Blautia_A 2.5%Clostridium 2.0%Thomasclavelia 1.7%Enterococcus 1.4%not assigned to a genus 2.7%other genera 15.4%

Genera, mean relative abundance over 449 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category352 65%
country538 100%538
health_condition0 0%
subject_id538 100%538
collection_date538 100%538
detailed_location538 100%
location_locality538 100%538
timepoint_label538 100%538
age_at_collection_days352 65%352
Papers (2)
  • Early life microbial succession in the gut follows common patterns in humans across the globe. 2025 PMID 39809768 PMC11733223 own_data
  • Infant gut microbiomes contribute to metabolic states that impact brain function 2026 own_data
Details
Archive description

Cork Nutrition Cohort for Infants

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site external_curation.infant_catalog · “infant triage verdict include (gut/stool scope)”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
  • life stage study.description · “Nutrition Cohort for Infants”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA115807788age_at_collection_days63.9R20.75paper.supp.41467_2025_56072_MOESM5_ESM.xlsx[Figure1B!ageMonths]CombineRun1_1036 2.0983606557377
SAMEA115807783collection_date2015-12-08R10.85biosample.attribute:collection_datecollection_date: 2015-12-08
SAMEA115807783countryIER10.90biosample_attrIreland
SAMEA115807783location_localityCorkR40.40ena.study_titleCork Nutrition Cohort
SAMEA115807783subject_id25R10.70sample.name_rule:title25_2
SAMEA115807783timepoint_label2R10.70sample.name_rule:title25_2
Sequencing

539 runs over 538 samples · mean 2.66 Gbp per run (median 2.33 Gbp, total 1,431.08 Gbp; 539 runs with a base count) · layout PAIRED 539 · platform ILLUMINA 539 · models NextSeq 2000 (539) · 83% of runs with a Sandpiper profile · first public 2025-01-02 – 2025-01-20

Authors (0)

No author record.

Downloads

PRJEB77202.csv.gz (20.3 KB) · parquet (96.3 KB) — all 538 samples, every field with route and confidence · PRJEB77202_determinations.csv.gz (27.8 KB) — 3,042 evidence rows

Samples (538 · every field this project has values for · hover a cell for its source)
Loading the sample table…