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PRJEB81237 ERP165085

Gut microbiota and colorectal cancer in China

Metabolites derived from the gut microbiota alleviate colorectal cancer

68 gut metagenome samples from China, studying bacterial metabolites from the gut microbiota and their relation to colorectal cancer tumor growth and progression. machine-written summary

69 samples · 69 runs · CN · Age unknown · 2026 · 10.49 Gbp / sample

Sources
✓Sequence archive 273–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive273 sample values (collection date, country, health condition, health condition detail)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

design observational_with_procedure

Samples at a glance
1 country
Age
unknown69
Condition
healthy_control36
colorectal_cancer32
Country
CN69
Body site
primary69
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 20 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 49 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 10.49 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country69 100%69
health_condition68 99%68
subject_id0 0%
collection_date68 99%68
health_condition_detail68 99%68
Details
Archive description

Bacterial metabolites derived from the gut microbiota can modulate key metabolic pathways, thereby influencing tumor growth and progression, which contributes to the alleviation of colorectal cancer. These metabolites play a crucial role in shaping the metabolic environment of the tumor, offering potential therapeutic strategies for managing colorectal cancer

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.60. Assay shotgun_dna.

  • host study.title · “Metabolites derived from the gut microbiota alleviate colorectal cancer”
  • body site run.scientific_name · “gut metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA116293762collection_date2023-04-29R10.90biosample.attribute:collection_date2023-04-29
SAMEA116293762countryCNR10.90sample.attr.geographic_location_country_and_or_seaChina
SAMEA116293762health_conditioncolorectal_cancerR10.85biosample.attribute:descriptiondescription: Stool sample of human from CRC
SAMEA116293762health_condition_detailStool sample of human from CRCR10.85biosample.attribute:descriptiondescription: Stool sample of human from CRC
Sequencing

69 runs over 69 samples · mean 11.05 Gbp per run (median 10.49 Gbp, total 762.19 Gbp; 69 runs with a base count) · layout PAIRED 69 · platform ILLUMINA 69 · models Illumina MiSeq (69) · 0% of runs with a Sandpiper profile · first public 2026-05-31

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJEB81237.csv.gz (2.5 KB) · parquet (72.1 KB) — all 69 samples, every field with route and confidence · PRJEB81237_determinations.csv.gz (2.0 KB) — 273 evidence rows

Samples (69 · every field this project has values for · hover a cell for its source)
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