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PRJEB96399 ERP179124

Gut metagenomes in IBS, Sweden, cross-sectional

Symptom Generation in Functional Bowel Disorders (SYMBOWL)

211 fecal metagenome samples from individuals with irritable bowel syndrome (IBS) in Sweden, collected as part of a cross-sectional study of host–microbiota interactions. machine-written summary

211 samples · 211 runs · SE · Age unknown · 2026 · 6.51 Gbp / sample

Sources
✓Sequence archive 422✓Abstract / description 422–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive422 sample values (collection date, country)
✓ Abstract / description422 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown211
Condition
ibs211
Country
SE211
Body site
primary211
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 210 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.51 Gbp per sample0130Gbp
Community composition
Faecalibacterium 6.9%Blautia_A 6.3%Roseburia 5.8%Bifidobacterium 4.9%Ruminococcoides 4.4%Bacteroides 4.3%Phocaeicola 3.4%Prevotella 2.9%Alistipes 2.7%Gemmiger 2.6%Collinsella 2.5%Fusicatenibacter 2.0%not assigned to a genus 4.6%other genera 46.7%

Genera, mean relative abundance over 210 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country211 100%211
health_condition211 100%211
subject_id0 0%
collection_date211 100%211
health_condition_detail211 100%211
Details
Archive description

Irritable bowel syndrome (IBS) is a gastrointestinal disorder characterized by recurrent abdominal pain and altered bowel habits. Alterations in gut microbiota and metabolites are thought to contribute to symptom development. This study uses fecal metagenomic sequencing and metabolomics to investigate host–microbiota interactions in IBS, generating datasets to support the identification of molecular mechanisms and potential therapeutic targets.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.80. Assay shotgun_dna.

  • host run.scientific_name · “Homo sapiens”
  • host study.description · “host–microbiota interactions in IBS”
  • body site study.description · “fecal metagenomic sequencing”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMEA120218446collection_date2015/2020R10.90biosample.attribute:collection_date2015/2020
SAMEA120218446countrySER10.90sample.attr.geographic_location_country_and_or_seaSweden
SAMEA120218446health_conditionibsR40.50study.descriptionIrritable bowel syndrome (IBS) is a gastrointestinal disorder
SAMEA120218446health_condition_detailIBS characterized by recurrent abdominal pain and altered bowel habitsR40.50study.descriptionIrritable bowel syndrome (IBS) is a gastrointestinal disorder
Sequencing

211 runs over 211 samples · mean 6.65 Gbp per run (median 6.51 Gbp, total 1,403.33 Gbp; 211 runs with a base count) · layout PAIRED 211 · platform ILLUMINA 211 · models Illumina NovaSeq 6000 (211) · 100% of runs with a Sandpiper profile · first public 2026-02-25

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJEB96399.csv.gz (5.7 KB) · parquet (76.9 KB) — all 211 samples, every field with route and confidence · PRJEB96399_determinations.csv.gz (4.4 KB) — 844 evidence rows

Samples (211 · every field this project has values for · hover a cell for its source)
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