Antibiotic effects on SCFAs with BB-12 probiotic, Baltimore
179 samples from Baltimore, USA, studying antibiotic-induced reduction in short-chain fatty acids and time-dependent administration of probiotic BB-12, as an intervention study. machine-written summary
179 samples · 179 runs · US · Age unknown · 2024 · 20.74 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,253 sample values (country, latitude, location locality, location region, longitude, subject id, timepoint) |
| – Abstract / description | no abstract or project description |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Probiotic (live microorganisms; single strain or mixture) · BB-12 probiotic administration, time-dependent, post-antibiotic
“time dependent administration of BB-12 proBIOTIC” — study.title (study level; per-sample arms are in the intervention column below)
longitudinal — not resolved
39 of 39 people sampled more than once (179 samples; median 5, up to 5 per person).
Genera, mean relative abundance over 163 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 179 | 100% | 179 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 179 | 100% | 179 | |||
| detailed_location | 179 | 100% | ||||
| latitude | 179 | 100% | 179 | |||
| location_locality | 179 | 100% | 179 | |||
| location_region | 179 | 100% | 179 | |||
| longitude | 179 | 100% | 179 | |||
| timepoint_label | 179 | 100% | 179 |
Archive description
Observing and Understanding antibiotic-induced Reduction in Short-chain Fatty Acids and time dependent administration of BB-12 proBIOTIC (OURBIOTIC)
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.65. Assay shotgun_dna.
- host run.scientific_name · “human gut metagenome”
- body site run.scientific_name · “human gut metagenome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN36996366 | country | US | R1 | 0.90 | sample.attr.geo_loc_name | USA: Baltimore |
| SAMN36996366 | latitude | 39.4393 | R1 | 0.90 | biosample.attribute:lat_lon | 39.43933024 N 76.56882640 W |
| SAMN36996366 | location_locality | Baltimore | R1 | 0.85 | biosample.attribute:geo_loc_name | USA: Baltimore |
| SAMN36996366 | location_region | Maryland | R1 | 0.60 | biosample.attribute:lat_lon | 39.43933024 N 76.56882640 W |
| SAMN36996366 | longitude | -76.5688 | R1 | 0.90 | biosample.attribute:lat_lon | 39.43933024 N 76.56882640 W |
| SAMN36996366 | subject_id | 106 | R1 | 0.70 | sample.name_rule:alias | O_106_14 |
| SAMN36996366 | timepoint_label | 14 | R1 | 0.70 | sample.name_rule:alias | O_106_14 |
Sequencing
179 runs over 179 samples · mean 20.71 Gbp per run (median 20.74 Gbp, total 3,707.78 Gbp; 179 runs with a base count) · layout PAIRED 179 · platform ILLUMINA 179 · models Illumina NovaSeq 6000 (179) · 91% of runs with a Sandpiper profile · first public 2024-02-20 – 2024-02-22
Authors (0)
No author record.
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata
Downloads
PRJNA1005702.csv.gz (5.4 KB) · parquet (75.9 KB) — all 179 samples, every field with route and confidence · PRJNA1005702_determinations.csv.gz (10.0 KB) — 1,253 evidence rows