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PRJNA1011937 SRP458371

Gut metagenomics in Chinese peri/post-menopausal women, Guangdong

Metagenomics of Chinese peri/post-menopausal women

499 fecal metagenome samples from healthy peri/post-menopausal women in Guangdong, China, cross-sectional, studying gut microbiota links to bone mineral density and osteoporosis risk. machine-written summary

499 samples · 499 runs · CN · Adult · 2023 · 7.01 Gbp / sample

Sources
✓Sequence archive 2,495✓Abstract / description 998–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive2,495 sample values (collection date, country, latitude, location region, longitude)
✓ Abstract / description998 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult499
Condition
healthy_control499
Country
CN499
Body site
primary499
Collected 2014–2018
2014: 57 samples2015: 167 samples2016: 148 samples2017: 124 samples2018: 3 samples20142018
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 477 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 22 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.01 Gbp per sample0130Gbp
Community composition
Phocaeicola 17.6%Bacteroides 15.3%Prevotella 9.1%Lachnospira 5.7%Faecalibacterium 5.2%Roseburia 3.6%Alistipes 2.7%Megamonas 1.9%Acetatifactor 1.8%Parabacteroides 1.4%Enterocloster 1.3%Phascolarctobacterium 1.1%not assigned to a genus 3.8%other genera 29.7%

Genera, mean relative abundance over 455 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category499 100%
country499 100%499
health_condition499 100%499
subject_id0 0%
collection_date499 100%499
detailed_location499 100%
health_condition_detail499 100%499
latitude499 100%499
location_region499 100%499
longitude499 100%499
Papers (1)
  • Gut microbiota impacts bone via Bacteroides vulgatus-valeric acid-related pathways. 2023 PMID 37891329 PMC10611739 unsure
Details
Archive description

Fecal samples from Chinese healthy peri/post-menopausal women and measured by metagenomics

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.description · “Fecal samples from Chinese”
  • body site external_curation.infant_catalog · “body_site_call gut”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • life stage study.title · “of Chinese peri/post-menopausal women”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN37275017collection_date2014-06-16R10.90biosample.attribute:collection_date2014-06-16
SAMN37275017countryCNR10.90sample.attr.geo_loc_nameChina: Guangdong
SAMN37275017health_conditionhealthy_controlR40.50study.descriptionChinese healthy peri/post-menopausal women
SAMN37275017health_condition_detailHealthy womenR40.50study.descriptionChinese healthy peri/post-menopausal women
SAMN37275017latitude20.3800R10.90biosample.attribute:lat_lon20.38 N 113.14 E
SAMN37275017location_regionGuangdongR10.85biosample.attribute:geo_loc_nameChina: Guangdong
SAMN37275017longitude113.1400R10.90biosample.attribute:lat_lon20.38 N 113.14 E
Sequencing

499 runs over 499 samples · mean 7.35 Gbp per run (median 7.01 Gbp, total 3,670.04 Gbp; 499 runs with a base count) · layout PAIRED 499 · platform ILLUMINA 499 · models Illumina HiSeq 4000 (499) · 91% of runs with a Sandpiper profile · first public 2023-09-08 – 2023-09-10

Authors (32)

Lin X first · Xiao HM · Liu HM · Lv WQ · Greenbaum J · Gong R · Zhang Q · Chen YC · Peng C · Xu XJ · Pan DY · Chen Z · Li ZF · Zhou R · Wang XF · Lu JM · Ao ZX · Song YQ · Zhang YH · Su KJ · Meng XH · Ge CL · Lv FY · Luo Z · Shi XM · Zhao Q · Guo BY · Yi NJ · Shen H · Papasian CJ · Shen J · Deng HW last

Downloads

PRJNA1011937.csv.gz (12.9 KB) · parquet (89.1 KB) — all 499 samples, every field with route and confidence · PRJNA1011937_determinations.csv.gz (18.7 KB) — 3,493 evidence rows

Samples (499 · every field this project has values for · hover a cell for its source)
Loading the sample table…