Pea protein + probiotic blend trial, healthy Indian men
30 fecal samples from 15 healthy Indian male adults in a randomized, double-blind, crossover trial comparing pea protein plus enzymes-probiotics blend versus placebo, assessing gut microbiota composition. machine-written summary
30 samples · 30 runs · IN · Age unknown · 2024 · 0.20 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 150 sample values (collection date, country, latitude, longitude, subject id) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 60 sample values (health condition, health condition detail) · PMC10844538 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal
15 of 15 people sampled more than once (30 samples; median 2, up to 2 per person) · follow-up median 14 d (max 14 d) · median interval between samples 14 d (time from visit codes mapped to the stated schedule). Schedule stated by the source: “Fecal samples collected on day 1 and day 15 of each supplementation period (test and placebo, crossover)” (time origin: intervention_start).
Each row is one person (15 shown); dots are samples at days since that person's first sample.
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 30 | 100% | ||||
| country | 30 | 100% | 30 | |||
| health_condition | 30 | 100% | 30 | |||
| subject_id | 30 | 100% | 30 | |||
| collection_date | 30 | 100% | 30 | |||
| health_condition_detail | 30 | 100% | 30 | |||
| latitude | 30 | 100% | 30 | |||
| longitude | 30 | 100% | 30 |
- Study of amino acids absorption and gut microbiome on consumption of pea protein blended with enzymes-probiotics supplement. 2024 PMID 38321993 PMC10844538 own_data
Archive description
A randomized, double-blind, crossover clinical trial was conducted on 15 healthy Indian male subjects. All the participants were randomly assigned to take either test product (pea protein + enzyme-probiotic blend) or placebo (pea protein + maltodextrin) for 15 days with 30 days of washout period. On day 1 and 15, blood samples were collected at 0, 0.5, 1, 2, 3 and 4 h post-supplementation to analyze the absorption of plasma amino acids. On day 15, blood samples from 0 h and 4 h were used to determine serum CRP and insulin levels. Urine and fecal nitrogen level was examined on day 1 and day 15. Additionally, fecal samples of the test subjects from day 1 and 15 were analyze for the microbiota composition.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.75. Assay shotgun_dna.
- host study.description · “15 healthy Indian male subjects”
- host run.host_tax_id · “9606”
- body site study.description · “fecal samples of the test subjects”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN37525400 | collection_date | 2021-12-02/2022-01-10 | R1 | 0.90 | biosample.attribute:collection_date | 2021-12-02/2022-01-10 |
| SAMN37525400 | country | IN | R1 | 0.90 | sample.attr.geo_loc_name | India |
| SAMN37525400 | health_condition | healthy_control | R3 | 0.70 | paper.fulltext.methods | 15 healthy adult subjects with an age range |
| SAMN37525400 | health_condition_detail | healthy adult subjects | R3 | 0.70 | paper.fulltext.methods | 15 healthy adult subjects with an age range |
| SAMN37525400 | latitude | 20.5937 | R1 | 0.90 | biosample.attribute:lat_lon | 20.5937 N 78.9629 E |
| SAMN37525400 | longitude | 78.9629 | R1 | 0.90 | biosample.attribute:lat_lon | 20.5937 N 78.9629 E |
| SAMN37525400 | subject_id | 1 | R1 | 0.70 | sample.name_rule:TITLE | TITLE: PP-Post 1 |
Sequencing
30 runs over 30 samples · mean 0.27 Gbp per run (median 0.20 Gbp, total 8.16 Gbp; 30 runs with a base count) · layout SINGLE 30 · platform OXFORD_NANOPORE 30 · models MinION (30) · 0% of runs with a Sandpiper profile · first public 2024-01-28
Authors (5)
Rathi A first · Gaonkar T · Dhar D · Kallapura G · Jadhav S last
Downloads
PRJNA1020557.csv.gz (1.6 KB) · parquet (70.8 KB) — all 30 samples, every field with route and confidence · PRJNA1020557_determinations.csv.gz (1.9 KB) — 210 evidence rows