Brain tumor, oral, fecal microbiome in cancer patients, Houston
655 samples from brain tumor, oral, and fecal sites in cancer patients (mostly other cancers, some colorectal cancer), largely from Houston, Texas, USA; cross-sectional design. machine-written summary
655 samples · 660 runs · US · Age unknown · 2024 · 1.56 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 3,596 sample values (collection date, country, health condition, health condition detail, latitude, location locality, location region, longitude) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC12618227, PMC13479879 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 88 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 471 | 72% | 471 | |||
| health_condition | 90 | 14% | 90 | |||
| subject_id | 590 | 90% | 590 | |||
| collection_date | 471 | 72% | 471 | |||
| detailed_location | 471 | 72% | ||||
| latitude | 471 | 72% | 471 | |||
| location_locality | 471 | 72% | 471 | |||
| location_region | 471 | 72% | 471 | |||
| longitude | 471 | 72% | 471 | |||
| health_condition_detail | 90 | 14% | 90 |
- Microbial signals in primary and metastatic brain tumors. 2025 PMID 41238915 PMC12618227 own_data
- Chronic stress unleashes an intratumor phage-fibroblast-B cell circuit to promote tumor growth. 2026 PMID 42349430 PMC13479879 own_data
Archive description
16S-amplicon and metagenomic sequencing of brain tumors and associated oral and fecal samples
How this project entered the registry
Classified as human blood / tissue / internal fluids / oral cavity / gut / stool mixed assays of age unknown by opus_adjudicated with confidence 0.55. Assay mixed.
- host run.host_tax_id · “9606”
- body site study.description · “brain tumors and associated oral and fecal samples”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN37650189 | collection_date | 2020-09/2022-10 | R1 | 0.90 | biosample.attribute:collection_date | 2020-09/2022-10 |
| SAMN37650189 | country | US | R1 | 0.90 | sample.attr.geo_loc_name | USA:Houston, Texas |
| SAMN50580585 | health_condition | other_cancer | R1 | 0.85 | biosample_attr | Ovarian Cancer |
| SAMN50580585 | health_condition_detail | Ovarian Cancer | R1 | 0.90 | sample.attr.primary_tumor | Ovarian Cancer |
| SAMN37650189 | latitude | 29.7604 | R1 | 0.90 | biosample.attribute:lat_lon | 29.7604 N 95.3698 W |
| SAMN37650189 | location_locality | Houston | R1 | 0.85 | biosample.attribute:geo_loc_name | USA:Houston, Texas |
| SAMN37650189 | location_region | Texas | R1 | 0.85 | biosample.attribute:geo_loc_name | USA:Houston, Texas |
| SAMN37650189 | longitude | -95.3698 | R1 | 0.90 | biosample.attribute:lat_lon | 29.7604 N 95.3698 W |
| SAMN37650189 | subject_id | 01-2020-06 | R1 | 0.70 | sample.name_rule:alias | 01-2020-06 |
| SAMN50580585 | subject_id | P47 | R1 | 0.85 | sample.attr.patient | P47 |
Sequencing
660 runs over 655 samples · mean 8.25 Gbp per run (median 1.67 Gbp, total 5,442.44 Gbp; 660 runs with a base count) · layout PAIRED 660 · platform ILLUMINA 660 · models Illumina NovaSeq 6000 (660) · 56% of runs with a Sandpiper profile · first public 2024-12-01 – 2025-11-23
Authors (88)
Morad G first · Damania AV · Melendez B · Singh BB · Veguilla FJ · Soto RA · Hoballah YM · Sahasrabhojane PV · Wong MC · Ahmed MM · Rico RN · Lewis KN · Wani K · Shamsutdinova DD · Lazcano Segura RN · Ingram DR · Goethe EA · Day A · Flores II · McDaniel LK · Chelvanambi M · Johnson SB · Dimitriou F · Gupta P · Oberai S · Zal MA · Doss P · Jamal MA · Hayase E · Wathoo C · Norberg LM · Jenkins SL · Nass S · Gumin J · Long L · Yang J · Bradley GR · Bekal MP · Dono AG · Pichardo-Rojas PS · Andrewes SW · Ballester LY · Losh JS · Liang J · Huo L · Nielsen DC · Parker Kerrigan BC · Brastianos PK · Fowlkes NW · Chang CC · Jenq RR · Gomez-Manzano C · Huse JT · Davies MA · Lazar AJ · Bhat KP · Tandon N · Esquenazi Y · Peterson CB · Puduvalli VK · Lang FF · Johnston CD · Bullman S · Ajami NJ · Ferguson SD · Wargo JA last · Bashir H first · Sanidad KZ · Ravisankar P · Banks KM · Bose A · Yu S · McGrath JJC · Carrow HC · Kim TK · Troxell CA · Brown JA · Hart LR · Goc J · Egeblad M · Chaudhuri J · Kim HS · Wilson PC · Lyden DC · Matei IR · Inohara N · Sonnenberg GF · Zeng MY last
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata
Downloads
PRJNA1023304.csv.gz (16.5 KB) · parquet (93.5 KB) — all 655 samples, every field with route and confidence · PRJNA1023304_determinations.csv.gz (25.8 KB) — 3,596 evidence rows