GDM and gut microbiome in mother-infant dyads, Hong Kong
A longitudinal cohort study of 1566 fecal samples from mother-baby dyads in Hong Kong, tracking gut microbiome trajectories in mothers during pregnancy and infants during the first year of life, in relation to gestational diabetes mellitus. machine-written summary
1,566 samples · 1,566 runs · HK · Infant / toddler · 2024 · 5.57 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,566 sample values (country) |
| ○ Abstract / description | read; no usable statement |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal — not resolvedmother–infant — not resolved
Schedule stated by the source: “Mothers sampled throughout pregnancy; infants sampled during first year of life; head circumference assessed at month 12”; stated follow-up 12 mo.
264 mother–baby dyads (per description); mothers sampled in pregnancy, infants in year 1; no per-sample dyad or role field in the archive.
Genera, mean relative abundance over 1,322 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 1,566 | 100% | 1,566 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% |
- Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring. 2024 PMID 38955186 own_data
Archive description
Utilizing the large-scale longitudinal fecal samples from 264 mother-baby dyads, we characterized the gut microbiome trajectory of the mothers during pregnancy and infants during the 1st year life.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of infant / toddler and adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage verdict include”
- body site study.description · “the large-scale longitudinal fecal samples from 264”
- body site external_curation.infant_catalog · “infant triage verdict include (gut/stool scope)”
- life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
- life stage study.title · “the maternal or infant microbiome trajectory”
- life stage study.title · “(GDM) impacts the maternal or infant microbiome”
- life stage study.description · “trajectory of the mothers during pregnancy and”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN38700329 | country | HK | R1 | 0.90 | biosample_attr | Hong Kong |
Sequencing
1,566 runs over 1,566 samples · mean 5.58 Gbp per run (median 5.57 Gbp, total 8,736.82 Gbp; 1,566 runs with a base count) · layout PAIRED 1,566 · platform ILLUMINA 1,566 · models Illumina NovaSeq 6000 (1,566) · 84% of runs with a Sandpiper profile · first public 2024-06-30
Authors (0)
No author record.
Help complete this project
3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata
Downloads
PRJNA1049511.csv.gz (39.0 KB) · parquet (133.0 KB) — all 1,566 samples, every field with route and confidence · PRJNA1049511_determinations.csv.gz (4.8 KB) — 1,566 evidence rows