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PRJNA1056831 SRP480054

Infant cholestasis gut microbiota case-control study in Taiwan

Microbiota of infant cholestasis in Taiwan

Gut microbiota data from 10 samples collected from infants with various types of cholestasis in Taiwan, using a case-control design. machine-written summary

10 samples · 10 runs · TW · Infant / toddler · 2024 · 8.42 Gbp / sample

Sources
✓Sequence archive 20○Abstract / description✓Full text 20○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive20 sample values (collection date, country)
○ Abstract / descriptionread; no usable statement
✓ Full text20 sample values (antibiotic exposure, location site) · PMC11246047
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown10
Country
TW10
Body site
primary10
Collected 2016–2021
2016: 1 samples2018: 3 samples2019: 1 samples2020: 2 samples2021: 3 samples20162021
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 10 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 8.42 Gbp per sample0130Gbp
Community composition
Klebsiella 23.9%Escherichia 20.3%Veillonella 19.5%Enterococcus_B 8.5%Phocaeicola 8.0%Bacteroides 7.4%Streptococcus 3.2%Bifidobacterium 1.8%Collinsella 1.5%Pauljensenia 1.0%Sutterella 0.6%Citrobacter_B 0.5%not assigned to a genus 2.0%other genera 2.0%

Genera, mean relative abundance over 10 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country10 100%10
health_condition0 0%
subject_id0 0%
antibiotic_exposure10 100%10
collection_date10 100%10
detailed_location10 100%
location_site10 100%10
Papers (1)
  • Gut <i>Bifidobacterium longum</i> is associated with better native liver survival in patients with biliary atresia. PMID 39006502 PMC11246047 curated
Details
Archive description

Microbiota sequence data of various types of infant cholestasis in Taiwan

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site external_curation.infant_catalog · “infant triage verdict include (gut/stool scope)”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
  • life stage study.title · “Microbiota of infant cholestasis in Taiwan”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN39109984antibiotic_exposureyesR30.50paper.fulltext.methodsall patients with BA received antibiotics
SAMN39109984collection_date2016-03-07R10.85biosample.attribute:collection_date2016-03-07
SAMN39109984countryTWR10.90biosample_attrTaiwan
SAMN39109984location_siteNational Taiwan University Children's HospitalR30.70paper.fulltext.methodsstudy was conducted at the National Taiwan University Children's Hospital
Sequencing

10 runs over 10 samples · mean 7.84 Gbp per run (median 8.42 Gbp, total 78.37 Gbp; 10 runs with a base count) · layout PAIRED 10 · platform ILLUMINA 10 · models Illumina NovaSeq 6000 (10) · 100% of runs with a Sandpiper profile · first public 2024-08-02

Authors (8)

Lee CS first · Lin CR · Chua HH · Wu JF · Chang KC · Ni YH · Chang MH · Chen HL last

Downloads

PRJNA1056831.csv.gz (1.2 KB) · parquet (69.8 KB) — all 10 samples, every field with route and confidence · PRJNA1056831_determinations.csv.gz (954 B) — 40 evidence rows

Samples (10 · every field this project has values for · hover a cell for its source)
Loading the sample table…