Gut virome of preterm infants, Guangdong, China
117 fecal virome samples from preterm infants within their first week of life in Guangdong, China, cross-sectionally profiled to examine associations between gut bacteriophage/virome composition and early-onset anemia or neurodevelopmental delay risk. machine-written summary
117 samples · 117 runs · CN · Neonate · 2025 · 10.74 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 682 sample values (collection date, country, latitude, location region, longitude, subject id) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 117 sample values (location locality) · PMC12510052 |
| ✓ Supplementary tables | 317 sample values (antibiotic exposure, health condition, health condition detail, sex) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal
10 of 107 people sampled more than once (20 samples; median 2, up to 2 per person) · follow-up median 3 d (max 5 mo) · median interval between samples 3 d (time from collection dates).
Each row is one person (5 shown of 10); dots are samples at days since that person's first sample.
Genera, mean relative abundance over 102 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 117 | 100% | ||||
| country | 117 | 100% | 117 | |||
| health_condition | 64 | 55% | 64 | |||
| subject_id | 117 | 100% | 117 | |||
| collection_date | 117 | 100% | 117 | |||
| detailed_location | 117 | 100% | ||||
| location_locality | 117 | 100% | 117 | |||
| location_region | 117 | 100% | 117 | |||
| latitude | 107 | 91% | 107 | |||
| longitude | 107 | 91% | 107 | |||
| sex | 107 | 91% | 107 | |||
| antibiotic_exposure | 82 | 70% | 82 | |||
| health_condition_detail | 64 | 55% | 64 |
- Gut virome characteristics associated with early onset of anemia and neurodevelopmental delay in preterm infants. 2025 PMID 41079634 PMC12510052 own_data
Archive description
Meta-virome sequencing of virus-like particles isolated from fecal samples of preterm infants within the first week of life
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of neonate by sonnet_x2 with confidence 0.72. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site run.scientific_name · “human gut metagenome”
- body site study.description · “fecal samples of preterm infants”
- life stage study.description · “preterm infants within the first week of life”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN39988202 | antibiotic_exposure | yes | R2 | 0.80 | paper.supp.mmc2.xlsx[Sheet1!antibioyn] | N-10141: antibioyn=1 |
| SAMN39988198 | collection_date | 2018-06-04 | R1 | 0.90 | biosample.attribute:collection_date | 2018-06-04 |
| SAMN39988198 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Guangdong |
| SAMN39988241 | health_condition | other_disease | R2 | 0.80 | paper.supp.mmc2.xlsx[Sheet1!Anemia] | A-10052: Anemia=1 |
| SAMN39988241 | health_condition_detail | Anemia=1 | R2 | 0.80 | paper.supp.mmc2.xlsx[Sheet1!Anemia] | A-10052: Anemia=1 |
| SAMN39988198 | latitude | 23.0500 | R1 | 0.90 | biosample.attribute:lat_lon | 23.05 N 113.11 E |
| SAMN39988198 | location_locality | Foshan | R3 | 0.70 | paper.fulltext.methods | neonatal intensive care unit (NICU) in Foshan Maternal Children's Hospital |
| SAMN39988198 | location_region | Guangdong | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Guangdong |
| SAMN39988198 | longitude | 113.1100 | R1 | 0.90 | biosample.attribute:lat_lon | 23.05 N 113.11 E |
| SAMN39988198 | sex | female | R2 | 0.80 | paper.supp.mmc2.xlsx[Sheet1!Gender] | N-10067: Gender=Female |
| SAMN39988198 | subject_id | N10067 | R1 | 0.70 | sample.name_rule:alias | N10067 |
Sequencing
117 runs over 117 samples · mean 13.43 Gbp per run (median 10.74 Gbp, total 1,571.00 Gbp; 117 runs with a base count) · layout PAIRED 117 · platform ILLUMINA 117 · models Illumina NovaSeq 6000 (117) · 93% of runs with a Sandpiper profile · first public 2025-03-03
Authors (10)
Ren S first · Zhang D · Shi X · Li T · Hu Q · Feng Y · Hu C · Feng S · Zhu Y · Gao F last
Downloads
PRJNA1078999.csv.gz (4.5 KB) · parquet (76.6 KB) — all 117 samples, every field with route and confidence · PRJNA1078999_determinations.csv.gz (9.7 KB) — 1,116 evidence rows