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PRJNA1082632 SRP492765

Gut microbiome of Indians, Indo-immigrants and Canadians

Indian Microbiome Project

Cross-sectional study of 174 stool samples from healthy adults (and one adolescent) in India and Canada, comparing gut microbiota of Indians, Indo-Immigrants, Indo-Canadians, and Euro-Canadian/Euro-Immigrant controls to assess effects of westernization. machine-written summary

174 samples · 174 runs · CA, IN · Adult · 2024 · 1.50 Gbp / sample

Sources
✓Sequence archive 977✓Abstract / description 174✓Full text 220○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive977 sample values (age, bmi, collection date, country, health condition, health condition detail, sex)
✓ Abstract / description174 sample values (subject id)
✓ Full text220 sample values (health condition, health condition detail) · PMC12317999
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
2 countries
Age
adult173
adolescent1
Condition
healthy_control174
Sex
female87
male87
Country
CA113
IN61
Body site
primary174
Collected 2017–2023
2017: 19 samples2018: 16 samples2019: 20 samples2022: 99 samples2023: 14 samples20172023
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 2 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 34 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 131 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 7 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.50 Gbp per sample0130Gbp
Community composition
Prevotella 9.5%Faecalibacterium 7.5%Roseburia 6.2%Bifidobacterium 4.6%Blautia_A 4.5%Phocaeicola 3.6%Bacteroides 3.4%Gemmiger 2.7%Alistipes 2.2%Dialister 2.1%Collinsella 1.8%Vescimonas 1.6%not assigned to a genus 14.3%other genera 36.0%

Genera, mean relative abundance over 124 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category174 100%
country174 100%174
health_condition174 100%64110
subject_id174 100%174
age_at_collection_days174 100%174
health_condition_detail174 100%64110
sex174 100%174
collection_date168 97%168
bmi159 91%159
Papers (1)
  • The adoption of a westernized gut microbiome in Indian Immigrants and Indo-Canadians is associated with dietary acculturation. 2025 PMID 40753175 PMC12317999 own_data
Details
Archive description

Our aim was to characterize the gut microbiome of Indians residing in India, Indian immigrants in Canada and Indians born in Canada (Indo-Canadians) to assess the role of immigration and westernization on the gut microbiome in Indian populations.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.75. Assay shotgun_dna.

  • host study.title · “Indian Microbiome Project”
  • host run.host_tax_id · “9606”
  • body site study.description · “characterize the gut microbiome of Indians”
  • body site run.scientific_name · “gut metagenome”
  • life stage sample.attr.host_age · “23 (n=173/174)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN40213846age_at_collection_days10601.0R10.85sample.attr.host_age29
SAMN40213847bmi26.23R10.90sample.attr.host_body_mass_index26.2345679
SAMN40213846collection_date2022-08-03R10.90biosample.attribute:collection_date2022-08-03
SAMN40213846countryCAR10.90sample.attr.geo_loc_nameCanada
SAMN40213895health_conditionhealthy_controlR10.85biosample.attribute:env_local_scaleenv_local_scale: Euro-Can
SAMN40213846health_conditionhealthy_controlR30.70paper.fulltext.methodsHealthy participants between the ages of 17–55 years
SAMN40213895health_condition_detailEuro-CanR10.85biosample.attribute:env_local_scaleenv_local_scale: Euro-Can
SAMN40213846health_condition_detailHealthy participants; exclusion of chronic inflammatory conditionR30.70paper.fulltext.methodsHealthy participants between the ages of 17–55 years
SAMN40213846sexfemaleR10.90sample.attr.host_sexfemale
SAMN40213846subject_idSAMN40213846R40.60design.one_sample_per_subject:abstractThis cross-sectional study examines the impact of westernization on the gut microbiomes of Indians
Sequencing

174 runs over 174 samples · mean 1.61 Gbp per run (median 1.50 Gbp, total 279.31 Gbp; 174 runs with a base count) · layout PAIRED 174 · platform ILLUMINA 174 · models Illumina NovaSeq 6000 (174) · 71% of runs with a Sandpiper profile · first public 2024-03-23

Authors (17)

D'Aloisio LD first · Ballal M · Ghosh S · Haskey N · Abulizi N · Karimianghadim R · Liu C · Sruthi P · Nagarajan L · Vasudevan S · Shetty V · Purandare M · Bhaumik U · Howlader DR · Pakpour S · Barnett J · Gibson DL last

Downloads

PRJNA1082632.csv.gz (7.0 KB) · parquet (80.1 KB) — all 174 samples, every field with route and confidence · PRJNA1082632_determinations.csv.gz (12.3 KB) — 1,371 evidence rows

Samples (174 · every field this project has values for · hover a cell for its source)
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