Gut microbiome, bile acids in hydatid disease, cirrhosis
151 samples from fecal and paired oral/fecal specimens of hydatid disease patients, liver cirrhosis patients, and healthy controls in Qinghai and Lanzhou, China, studying bile acid–gut microbiome interactions; cross-sectional design. machine-written summary
151 samples · 151 runs · CN · Age unknown · 2025 · 6.48 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 625 sample values (collection date, country, health condition, health condition detail, location locality, location region) |
| ✓ Abstract / description | 65 sample values (health condition detail) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 150 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 151 | 100% | 151 | |||
| health_condition | 86 | 57% | 86 | |||
| subject_id | 0 | 0% | ||||
| collection_date | 151 | 100% | 151 | |||
| detailed_location | 151 | 100% | ||||
| health_condition_detail | 151 | 100% | 86 | 65 | ||
| location_region | 104 | 69% | 104 | |||
| location_locality | 47 | 31% | 47 |
Archive description
Human fecal samples from hydatid patients, liver cirrhosis patients, and healthy controls (shortgun). Paired oral and fecal samples from patients with hydatid disease and cirrhosis (full-length 16S). Transcriptomes of S. anginosus cultures and liver tissues from Echinococcus-infected mice (bulk RNA-seq).
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.57. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site run.scientific_name · “gut metagenome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN48326014 | collection_date | 2023-01 | R1 | 0.90 | biosample.attribute:collection_date | 2023-01 |
| SAMN48326014 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China:Lanzhou |
| SAMN48326014 | health_condition | liver_disease | R1 | 0.70 | sample.name_rule:sample_alias | L31 |
| SAMN48326014 | health_condition_detail | L | R1 | 0.70 | sample.name_rule:sample_alias | L31 |
| SAMN48329024 | health_condition_detail | mixed_case_control: hydatid disease and liver cirrhosis patients versus healthy controls | R4 | 0.50 | study.description | hydatid patients, liver cirrhosis patients, and healthy controls |
| SAMN48326014 | location_locality | Lanzhou | R1 | 0.85 | biosample.attribute:geo_loc_name | China:Lanzhou |
| SAMN48329024 | location_region | Qinghai | R1 | 0.85 | biosample.attribute:geo_loc_name | China:Qinghai |
Sequencing
151 runs over 151 samples · mean 6.47 Gbp per run (median 6.48 Gbp, total 976.48 Gbp; 151 runs with a base count) · layout PAIRED 151 · platform ILLUMINA 151 · models Illumina NovaSeq 6000 (151) · 99% of runs with a Sandpiper profile · first public 2025-10-01 – 2025-10-23
Authors (0)
No author record.
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata
Downloads
PRJNA1092365.csv.gz (4.3 KB) · parquet (75.5 KB) — all 151 samples, every field with route and confidence · PRJNA1092365_determinations.csv.gz (5.2 KB) — 690 evidence rows