Gut microbiome in pregnancy complications, Detroit (case-control)
Case-control study of 250 rectal swab samples from pregnant adults in Detroit, USA, comparing term birth, preterm birth, and preeclampsia to assess gut microbiome contributions to these outcomes. machine-written summary
250 samples · 250 runs · US · Adult · 2025 · 6.69 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,250 sample values (collection date, country, latitude, location locality, longitude) |
| ○ Abstract / description | read; no usable statement |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 209 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 250 | 100% | ||||
| country | 250 | 100% | 250 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% | ||||
| collection_date | 250 | 100% | 250 | |||
| detailed_location | 250 | 100% | ||||
| latitude | 250 | 100% | 250 | |||
| location_locality | 250 | 100% | 250 | |||
| longitude | 250 | 100% | 250 |
Archive description
Metagenomic sequencing of rectal swabs from pregnant women experiencing term birth, preterm birth, or preeclampsia. Sequencing was performed to assess the potential contributions of the gut microbiome to these clinical outcomes.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult and neonate by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_maternal_only”
- body site study.title · “Gut Microbiome and Pregnancy”
- body site study.description · “Metagenomic sequencing of rectal swabs from pregnant”
- life stage external_curation.infant_catalog · “infant triage reason_code age_maternal_only”
- life stage study.description · “rectal swabs from pregnant women experiencing term birth,”
- life stage study.description · “experiencing term birth, preterm birth, or preeclampsia.”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN40933101 | collection_date | 2016/2020 | R1 | 0.90 | biosample.attribute:collection_date | 2016/2020 |
| SAMN40933101 | country | US | R1 | 0.90 | sample.attr.geo_loc_name | USA: Detroit |
| SAMN40933101 | latitude | 37.3667 | R1 | 0.90 | biosample.attribute:lat_lon | 37.36666 N 80.53333 W |
| SAMN40933101 | location_locality | Detroit | R1 | 0.85 | biosample.attribute:geo_loc_name | USA: Detroit |
| SAMN40933101 | longitude | -80.5333 | R1 | 0.90 | biosample.attribute:lat_lon | 37.36666 N 80.53333 W |
Sequencing
250 runs over 250 samples · mean 9.04 Gbp per run (median 6.69 Gbp, total 2,260.24 Gbp; 250 runs with a base count) · layout PAIRED 250 · platform ILLUMINA 250 · models Illumina NovaSeq 6000 (250) · 84% of runs with a Sandpiper profile · first public 2025-04-27
Authors (0)
No author record.
Help complete this project
2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata
Downloads
PRJNA1099236.csv.gz (6.7 KB) · parquet (78.5 KB) — all 250 samples, every field with route and confidence · PRJNA1099236_determinations.csv.gz (6.8 KB) — 1,250 evidence rows