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PRJNA1112983 SRP509929

Kawasaki disease patient stool metagenome, Chengdu, China

Kawasaki diseases patients metagenome Raw sequence reads

202 stool samples from Kawasaki disease patients in Chengdu, China, profiled by shotgun metagenomic sequencing; no further design or intervention details are given. machine-written summary

202 samples · 202 runs · CN · Infant / toddler · 2024 · 10.63 Gbp / sample

Sources
✓Sequence archive 404✓Abstract / description 202✓Full text 202○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive404 sample values (collection date, country)
✓ Abstract / description202 sample values (health condition)
✓ Full text202 sample values (location site) · PMC11298399
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown202
Condition
other_disease202
Country
CN202
Body site
primary202
Collected 2022–2023
2022: 30 samples2023: 172 samples20222023
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 14 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 188 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 10.63 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

Schedule stated by the source: “Stool collected at diagnosis (before IVIG) and again at 36h after initial IVIG administration”; stated follow-up 2 d.

How longitudinal and relatedness information is derived

Community composition
Prevotella 11.8%Bacteroides 8.3%Bifidobacterium 7.6%Enterococcus_B 4.8%Phocaeicola 3.6%Escherichia 3.1%Anaerococcus 2.5%Streptococcus 2.5%Porphyromonas 2.4%Veillonella 2.4%Finegoldia 2.3%Porphyromonas_A 2.0%not assigned to a genus 7.1%other genera 39.5%

Genera, mean relative abundance over 182 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country202 100%202
health_condition202 100%202
subject_id0 0%
collection_date202 100%202
detailed_location202 100%
location_site202 100%202
Papers (1)
  • Metagenomic analysis demonstrates distinct changes in the gut microbiome of Kawasaki diseases children. 2024 PMID 39104524 PMC11298399 own_data
Details
Archive description

normal DNA-seq of the stool of Kawasaki diseases patients

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site study.description · “DNA-seq of the stool of Kawasaki diseases”
  • body site external_curation.infant_catalog · “infant triage verdict include (gut/stool scope)”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN41445359collection_date2023-01-10R10.85biosample.attribute:collection_date2023-01-10
SAMN41445359countryCNR10.90biosample_attrChina:Chengdu
SAMN41445359health_conditionother_diseaseR40.40study.titleKawasaki diseases patients metagenome
SAMN41445359location_siteWest China Second University Hospital of Sichuan UniversityR30.70paper.fulltext.methods_resultsThe participants involved in this research had been enrolled from the West China Second University Hospital of Sichuan University from August 2022 to June 2023.
Sequencing

202 runs over 202 samples · mean 10.89 Gbp per run (median 10.63 Gbp, total 2,199.01 Gbp; 202 runs with a base count) · layout PAIRED 202 · platform ILLUMINA 202 · models Illumina NovaSeq 6000 (202) · 90% of runs with a Sandpiper profile · first public 2024-05-26

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJNA1112983.csv.gz (6.4 KB) · parquet (78.9 KB) — all 202 samples, every field with route and confidence · PRJNA1112983_determinations.csv.gz (5.4 KB) — 808 evidence rows

Samples (202 · every field this project has values for · hover a cell for its source)
Loading the sample table…