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PRJNA1116923 SRP510487

Prevotella Dynamics in Healthy Chinese Gut Microbiota

Human Gut Microbiota

429 fecal samples from healthy individuals in Beijing, Henan, Jiangsu, and Sichuan, China, examining temporal and geographic dynamics of Prevotella spp. in the gut microbiota; longitudinal design. machine-written summary

429 samples · 429 runs · CN · Age unknown · 2024 · 0.22 Gbp / sample · cohort Dynamic change patterns of the human gut microbiot

One study deposited as 2 BioProjects (516 catalog samples together): PRJNA1116923 · PRJNA1215598 · show together

Sources
✓Sequence archive 1,765✓Abstract / description 858○Full text✓Supplementary tables 797–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive1,765 sample values (collection date, country, latitude, location locality, location region, longitude)
✓ Abstract / description858 sample values (health condition, health condition detail)
○ Full textread; no usable statement or table · PMC11265296, PMC13064649
✓ Supplementary tables797 sample values (antibiotic exposure, sex, subject id, timepoint)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown429
Condition
healthy_control429
Sex
female273
male101
Country
CN429
Body site
primary429
Collected 2016–2022
2016: 79 samples2017: 104 samples2018: 102 samples2019: 42 samples2020: 29 samples2021: 34 samples2022: 39 samples20162022
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 1 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 1 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 3 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 358 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 66 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.58 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

7 of 7 people sampled more than once (239 samples; median 35, up to 46 per person). Schedule stated by the source: “cross-sectional n=190; 52 monthly time points over 2017-2022 for n=7; paired 0 and 6 months for n=43”.

How longitudinal and relatedness information is derived

Community composition
Phocaeicola 21.0%Prevotella 18.5%Bacteroides 16.3%Alistipes 4.9%Faecalibacterium 4.5%Roseburia 3.0%Gemmiger 1.4%Lachnospira 1.3%Parabacteroides 1.2%Acetatifactor 1.2%Sutterella 1.2%Oscillibacter 1.0%not assigned to a genus 3.8%other genera 20.8%

Genera, mean relative abundance over 385 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country429 100%429
health_condition429 100%429
subject_id239 56%239
collection_date429 100%429
detailed_location429 100%
health_condition_detail429 100%429
sex374 87%374
location_locality341 79%341
latitude239 56%239
longitude239 56%239
antibiotic_exposure129 30%129
location_region88 21%88
timepoint_label55 13%55
Papers (2)
  • Temporal dynamics and species-level complexity of Prevotella spp. in the human gut microbiota: implications for enterotypes and health. 2024 PMID 39044948 PMC11265296 own_data
  • Dynamic change patterns of the human gut microbiota-fluctuation, loss-acquisition, and turnover-and their underlying causes. 2026 PMID 41971531 PMC13064649 own_data
Details
Archive description

Chinese Healthy Gut Microbiota

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site run.scientific_name · “feces metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN41553299antibiotic_exposureyesR20.80paper.supp.supplementary_material_ycag046.zip/Supplemental Table1.xlsx[Sheet1!Antibiotic]Drug+
SAMN41553299collection_date2017R10.90biosample.attribute:collection_date2017
SAMN41553299countryCNR10.90sample.attr.geo_loc_nameChina:Beijing
SAMN41553299health_conditionhealthy_controlR40.50study.descriptionChinese Healthy Gut Microbiota
SAMN41553299health_condition_detailHealthy individualsR40.50study.descriptionChinese Healthy Gut Microbiota
SAMN41553299latitude39.5400R10.90biosample.attribute:lat_lon39.54 N 116.23 E
SAMN41553299location_localityBeijingR10.85biosample.attribute:geo_loc_nameChina:Beijing
SAMN44930030location_regionSichuanR10.85biosample.attribute:geo_loc_nameChina:Sichuan
SAMN41553299longitude116.2300R10.90biosample.attribute:lat_lon39.54 N 116.23 E
SAMN41553299sexfemaleR20.80paper.supp.supplementary_material_ycag046.zip/Supplemental Table1.xlsx[Sheet1!Gendor]Female
SAMN41553299subject_idP1R20.80paper.supp.supplementary_material_ycag046.zip/Supplemental Table1.xlsx[Sheet1!People/Location]P1
SAMN41553483timepoint_label2021_06R20.80paper.supp.supplementary_material_ycag046.zip/Supplemental Table1.xlsx[Sheet1!Time]S21ZYF1 CMP_multi-time P1 2021_06
Sequencing

429 runs over 429 samples · mean 3.84 Gbp per run (median 0.22 Gbp, total 1,645.53 Gbp; 429 runs with a base count) · layout PAIRED 426, SINGLE 3 · platform ILLUMINA 429 · models Illumina HiSeq 2000 (429) · 68% of runs with a Sandpiper profile · first public 2024-06-02 – 2024-12-01

Authors (7)

Han N first · Peng X · Zhang T · Qiang Y · Li X · Zhang W last · Kan B last

Downloads

PRJNA1116923.csv.gz (10.7 KB) · parquet (85.4 KB) — all 429 samples, every field with route and confidence · PRJNA1116923_determinations.csv.gz (18.4 KB) — 3,420 evidence rows

Samples (429 · every field this project has values for · hover a cell for its source)
Loading the sample table…