Gut microbiome obesity index in obese vs healthy adults, Poland
Shotgun metagenomic sequencing of stool from 91 adults in Poland (63 obesity, 28 healthy controls) used to derive a taxonomy- and function-based gut microbiome obesity index correlated with BMI. machine-written summary
91 samples · 91 runs · PL · Age unknown · 2024 · 3.95 Gbp / sample · cohort Microbial and Metabolic Gut Profiling across Seven
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 528 sample values (age, bmi, country, health condition, health condition detail, sex) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 91 sample values (antibiotic exposure) · PMC12298630 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 91 | 100% | ||||
| country | 91 | 100% | 91 | |||
| health_condition | 91 | 100% | 91 | |||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 91 | 100% | 91 | |||
| antibiotic_exposure | 91 | 100% | 91 | |||
| bmi | 91 | 100% | 91 | |||
| health_condition_detail | 91 | 100% | 91 | |||
| sex | 73 | 80% | 73 |
- The Gut Microbiome Obesity Index: A New Analytical Tool in the Metagenomics Workflow for the Evaluation of Gut Dysbiosis in Obese Humans 2025 PMID 40732945 PMC12298630 own_data
Archive description
Having access to stool samples from obese people with a wide range of obesity, we analyzed metagenomics data using a standard analytical pipeline previously used in our research, and the results obtained allowed us to create a new method of analysis, named the gut microbiome obesity index, using a set of taxa whose relative abundances correlated with the degree of obesity
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by curator_audit with confidence 0.60. Assay shotgun_dna.
- host runs.scientific_name · “human gut metagenome”
- host papers[0].abstract · “whole-genome shotgun sequencing”
- body site runs.scientific_name · “human gut metagenome”
- body site papers[0].abstract · “whole-genome shotgun sequencing”
- life stage sample.attr.host_age · “30 (n=84/91)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN41913554 | age_at_collection_days | 10957.5 | R1 | 0.85 | sample.attr.host_age | 30 |
| SAMN41913563 | age_at_collection_days | 18262.5 | R1 | 0.85 | biosample.attribute:host_age | host_age: 50 |
| SAMN41913554 | antibiotic_exposure | no | R3 | 0.70 | paper.body.PMC12298630 | None of the participants had used antibiotics in the 2 months before fecal sampling |
| SAMN41913554 | bmi | 20.31 | R1 | 0.85 | biosample.attribute:host_body_mass_index | host_body_mass_index: 20.3125 |
| SAMN41913554 | country | PL | R1 | 0.90 | sample.attr.geo_loc_name | Poland:Warsaw |
| SAMN41913554 | health_condition | healthy_control | R1 | 0.85 | biosample.attribute:host_disease | host_disease: control |
| SAMN41913554 | health_condition_detail | control | R1 | 0.85 | biosample.attribute:host_disease | host_disease: control |
| SAMN41913554 | sex | female | R1 | 0.90 | sample.attr.host_sex | female |
Sequencing
91 runs over 91 samples · mean 4.48 Gbp per run (median 3.95 Gbp, total 407.79 Gbp; 91 runs with a base count) · layout PAIRED 91 · platform ILLUMINA 91 · models Illumina NovaSeq 6000 (91) · 95% of runs with a Sandpiper profile · first public 2024-06-30 – 2024-07-29
Authors (0)
No author record.
Downloads
PRJNA1125836.csv.gz (3.7 KB) · parquet (74.3 KB) — all 91 samples, every field with route and confidence · PRJNA1125836_determinations.csv.gz (6.3 KB) — 619 evidence rows