Gut Virome in First-Episode Schizophrenia, China (Case-Control)
98 gut metagenome samples from adults in China, comparing first-episode schizophrenia patients (49 samples) and matched healthy controls (49 samples) in a case-control design to study viral patterns linked to schizophrenia. machine-written summary
98 samples · 98 runs · CN · Adult · 2024 · 12.15 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 686 sample values (collection date, country, health condition, health condition detail, latitude, location region, longitude) |
| ✓ Abstract / description | 98 sample values (subject id) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 86 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 98 | 100% | ||||
| country | 98 | 100% | 98 | |||
| health_condition | 98 | 100% | 98 | |||
| subject_id | 98 | 100% | 98 | |||
| collection_date | 98 | 100% | 98 | |||
| detailed_location | 98 | 100% | ||||
| health_condition_detail | 98 | 100% | 98 | |||
| latitude | 98 | 100% | 98 | |||
| location_region | 98 | 100% | 98 | |||
| longitude | 98 | 100% | 98 |
- Gut virome alterations in schizophrenia: identifying viral biomarkers associated with schizophrenia and treatment response. 2025 PMID 40835054 own_data
Archive description
This project investigated the gut virome of 49 first-episode schizophrenia patients and 49 matched healthy controls using metagenomic sequencing. The aim is to identify viral patterns associated with schizophrenia, enhancing our understanding of the virome's role in this condition.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “Gut Virome in First-Episode”
- body site study.description · “project investigated the gut virome of 49”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN42484525 | collection_date | 2022 | R1 | 0.90 | biosample.attribute:collection_date | 2022 |
| SAMN42484525 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China |
| SAMN42484525 | health_condition | neurological_psychiatric | R1 | 0.90 | biosample_attr | schizophrenia |
| SAMN42484525 | health_condition_detail | schizophrenia | R1 | 0.90 | sample.attr.host_disease | schizophrenia |
| SAMN42484525 | latitude | 30.6700 | R1 | 0.90 | biosample.attribute:lat_lon | 30.67 N 104.06 E |
| SAMN42484525 | location_region | Sichuan | R1 | 0.60 | biosample.attribute:lat_lon | 30.67 N 104.06 E |
| SAMN42484525 | longitude | 104.0600 | R1 | 0.90 | biosample.attribute:lat_lon | 30.67 N 104.06 E |
| SAMN42484525 | subject_id | SAMN42484525 | R4 | 0.60 | design.one_sample_per_subject:abstract | metagenomic sequencing on fecal samples from 49 first-episode schizophrenia patients and 49 healthy controls |
Sequencing
98 runs over 98 samples · mean 12.62 Gbp per run (median 12.15 Gbp, total 1,236.74 Gbp; 98 runs with a base count) · layout PAIRED 98 · platform ILLUMINA 98 · models Illumina NovaSeq 6000 (98) · 88% of runs with a Sandpiper profile · first public 2024-07-23
Authors (0)
No author record.
Downloads
PRJNA1135500.csv.gz (3.4 KB) · parquet (74.5 KB) — all 98 samples, every field with route and confidence · PRJNA1135500_determinations.csv.gz (4.9 KB) — 784 evidence rows