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PRJNA1138246 SRP521153

Longitudinal fecal metagenomes of healthy Peruvian infants

Fecal metagenomes of Peruvian children

298 fecal metagenome samples from healthy infants in peri-urban Lima, Peru, collected longitudinally between 3-16 months of age as part of a cohort study of enteric infections. machine-written summary

298 samples · 298 runs · PE · Infant / toddler · 2025 · 8.10 Gbp / sample

Sources
✓Sequence archive 596✓Abstract / description 298✓Full text 894✓Supplementary tables 596–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive596 sample values (collection date, country)
✓ Abstract / description298 sample values (health condition)
✓ Full text894 sample values (location locality, location region, preterm status) · PMC12323407
✓ Supplementary tables596 sample values (age, subject id)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
infant298
Condition
healthy_control298
Country
PE298
Body site
primary298
Collected 2017–2018
2017: 206 samples2018: 92 samples20172018
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 3 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 248 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 47 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 8.10 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

54 of 54 people sampled more than once (298 samples; median 6, up to 6 per person) · follow-up median 13 mo (max 13 mo) · median interval between samples 3 mo (time from age at collection). Schedule stated by the source: “Longitudinal fecal sampling of same children from 3 to 16 months of age; exact intervals not stated.”.

11: day 01: day 921: day 1221: day 1831: day 2741: day 3961010: day 010: day 9210: day 12210: day 18310: day 27410: day 3961111: day 011: day 9211: day 12211: day 18311: day 27411: day 3961212: day 012: day 12212: day 18312: day 27412: day 3961313: day 013: day 9213: day 18313: day 27413: day 3961414: day 014: day 9214: day 18314: day 27414: day 3961515: day 015: day 9215: day 18315: day 27415: day 3961616: day 016: day 9216: day 12216: day 18316: day 27416: day 3961717: day 017: day 9217: day 12217: day 18317: day 27417: day 3961818: day 018: day 9218: day 12218: day 18318: day 27418: day 3961919: day 019: day 9219: day 12219: day 18319: day 27419: day 3962121: day 021: day 9221: day 12221: day 18321: day 27421: day 3962222: day 022: day 9222: day 12222: day 18322: day 27422: day 3962424: day 024: day 9224: day 12224: day 18324: day 27424: day 3962626: day 026: day 9226: day 12226: day 18326: day 27426: day 3962727: day 027: day 9227: day 12227: day 18327: day 27427: day 3962828: day 028: day 9228: day 12228: day 18328: day 27428: day 3962929: day 029: day 9229: day 12229: day 18329: day 27429: day 39633: day 03: day 923: day 1223: day 1833: day 2743: day 3963131: day 031: day 9231: day 12231: day 18331: day 27431: day 3963434: day 034: day 9234: day 12234: day 18334: day 27434: day 3963535: day 035: day 9235: day 12235: day 18335: day 27435: day 3963737: day 037: day 9237: day 12237: day 18337: day 27437: day 3963838: day 038: day 9238: day 12238: day 18338: day 27438: day 39644: day 04: day 924: day 1224: day 1834: day 2744: day 3964040: day 040: day 9240: day 12240: day 18340: day 27440: day 3964343: day 043: day 9243: day 12243: day 18343: day 27443: day 3964545: day 045: day 9245: day 12245: day 18345: day 27445: day 3964646: day 046: day 9246: day 12246: day 18346: day 27446: day 3964747: day 047: day 9247: day 12247: day 18347: day 27447: day 3964949: day 049: day 9249: day 12249: day 18349: day 27449: day 39655: day 05: day 925: day 1225: day 1835: day 2745: day 3965252: day 052: day 9252: day 12252: day 18352: day 27452: day 3965353: day 053: day 9253: day 12253: day 18353: day 27453: day 3965454: day 054: day 9254: day 12254: day 18354: day 27454: day 39677: day 07: day 927: day 1227: day 1837: day 2747: day 3960 d3 mo7 mo10 mo13 mo

Each row is one person (36 shown of 54); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition
Bifidobacterium 63.9%Streptococcus 3.2%Mediterraneibacter 3.0%Blautia_A 2.6%Faecalibacterium 2.4%Collinsella 1.8%Escherichia 1.6%Bacteroides 1.2%Prevotella 1.1%Megasphaera 0.9%Ligilactobacillus 0.9%Veillonella 0.8%not assigned to a genus 2.8%other genera 14.0%

Genera, mean relative abundance over 293 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category298 100%
country298 100%298
health_condition298 100%298
subject_id298 100%298
age_at_collection_days298 100%298
collection_date298 100%298
detailed_location298 100%
location_locality298 100%298
location_region298 100%298
preterm_status298 100%298
Papers (1)
  • Role of the gut microbiome in frequent gut colonization with extended-spectrum β lactamase-producing Enterobacterales among Peruvian children. PMID 40755247 PMC12323407 curated
Details
Archive description

Fecal metagenomes from 54 healthy children living in peri-urban Lima, sampled longitudinally from 3-16 months. Children participated in an cohort study of enteric infections from 2016-2019 (NIH R01AI108695-01A )

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of child and infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site study.title · “Fecal metagenomes of Peruvian”
  • body site study.description · “Fecal metagenomes from 54”
  • life stage study.title · “metagenomes of Peruvian children”
  • life stage study.description · “from 54 healthy children living in peri-urban”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN42686832age_at_collection_days91R20.85paper.supp.tableRounded child age (months)=3
SAMN42686832collection_date2017-01-02R10.85biosample.attribute:collection_date2017-01-02T15:02:00Z
SAMN42686832countryPER10.90biosample_attrPeru: Lima
SAMN42686832health_conditionhealthy_controlR40.45study.description54 healthy children living in peri-urban Lima
SAMN42686832location_localityVilla El SalvadorR30.70paper.fulltext.methodsVilla El Salvador, Lima, Peru
SAMN42686832location_regionLimaR30.70paper.fulltext.methodsVilla El Salvador, Lima, Peru
SAMN42686832preterm_statustermR30.80paper.fulltext.methodsFull-term babies were enrolled no later than 4 weeks
SAMN42686832subject_id3R20.85paper.supp.tableChild ID=3
Sequencing

298 runs over 298 samples · mean 7.88 Gbp per run (median 8.10 Gbp, total 2,348.60 Gbp; 298 runs with a base count) · layout PAIRED 298 · platform ILLUMINA 298 · models Illumina NovaSeq 6000 (298) · 98% of runs with a Sandpiper profile · first public 2025-07-16

Authors (9)

Nadimpalli ML first · Sehgal N · Rojas-Salvatierra L · Gilman RH · Earl AM · Worby CJ · Schwab M · Pickering AJ · Pajuelo MJ last

Downloads

PRJNA1138246.csv.gz (10.8 KB) · parquet (83.7 KB) — all 298 samples, every field with route and confidence · PRJNA1138246_determinations.csv.gz (18.2 KB) — 2,384 evidence rows

Samples (298 · every field this project has values for · hover a cell for its source)
Loading the sample table…