Gut metagenome of GDM vs NGT pregnancies, diet intervention
65 stool samples from pregnant women with gestational diabetes (GDM) or normal glucose tolerance (NGT), studied before and after lifestyle/diet intervention for glycemic control. machine-written summary
65 samples · 65 runs · CN · Adult · 2024 · 12.97 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 260 sample values (collection date, health condition, health condition detail, subject id) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 195 sample values (country, location site, sex) · PMC11622461 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Controlled / prescribed diet or feeding regimen design single_arm_before_after · population pregnancy_postpartum · Lifestyle/glycemic control management (diet) in GDM pregnancies
“before and after glycemic control” — abstract:39643877 (study level; per-sample arms are in the intervention column below)
Genera, mean relative abundance over 61 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 65 | 100% | ||||
| country | 65 | 100% | 65 | |||
| health_condition | 65 | 100% | 65 | |||
| subject_id | 65 | 100% | 65 | |||
| collection_date | 65 | 100% | 65 | |||
| detailed_location | 65 | 100% | ||||
| health_condition_detail | 65 | 100% | 65 | |||
| location_site | 65 | 100% | 65 | |||
| sex | 65 | 100% | 65 |
- Bifidobacterium species serve as key gut microbiome regulators after intervention in gestational diabetes mellitus. 2024 PMID 39643877 PMC11622461 own_data
Archive description
Metagenome sequencing on stool samples of GDM and NGT pregnancies
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_maternal_only”
- body site study.title · “human gut metagenome data of”
- body site study.description · “Metagenome sequencing on stool samples of GDM”
- life stage external_curation.infant_catalog · “infant triage reason_code age_maternal_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN44667032 | collection_date | 2017 | R1 | 0.90 | biosample.attribute:collection_date | 2017 |
| SAMN44667032 | country | CN | R3 | 0.70 | paper.fulltext.methods | Peking University First Hospital |
| SAMN44667032 | health_condition | healthy_control | R1 | 0.70 | sample.name_rule:alias | N393 |
| SAMN44667032 | health_condition_detail | N | R1 | 0.70 | sample.name_rule:alias | N393 |
| SAMN44667032 | location_site | Peking University First Hospital | R3 | 0.70 | paper.fulltext.methods | nested case‒control study at Peking University First Hospital |
| SAMN44667032 | sex | female | R3 | 0.70 | paper.fulltext.methods | Pregnant women were enrolled in the first trimester |
| SAMN44667032 | subject_id | N393 | R1 | 0.85 | biosample.attribute:alias | alias: N393 |
Sequencing
65 runs over 65 samples · mean 13.01 Gbp per run (median 12.97 Gbp, total 845.42 Gbp; 65 runs with a base count) · layout PAIRED 65 · platform ILLUMINA 65 · models Illumina HiSeq 2000 (65) · 94% of runs with a Sandpiper profile · first public 2024-12-29
Downloads
PRJNA1142935.csv.gz (2.6 KB) · parquet (73.1 KB) — all 65 samples, every field with route and confidence · PRJNA1142935_determinations.csv.gz (4.2 KB) — 455 evidence rows