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PRJNA1148078 SRP540496

Gut microbiome in Taenia asiatica infection, Dali, China

Human fecal samples Metagenome

190 fecal samples from a case-control study in Dali, China, comparing gut microbiota of Taenia asiatica-infected patients and healthy controls, including a longitudinal subset sampled after deworming. machine-written summary

190 samples · 190 runs · CN · Age unknown · 2024 · 11.46 Gbp / sample

Sources
✓Sequence archive 755✓Abstract / description 190✓Full text 190○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive755 sample values (collection date, country, location locality, subject id, timepoint)
✓ Abstract / description190 sample values (health condition detail)
✓ Full text190 sample values (antibiotic exposure) · PMC11536184
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

design single_arm_before_after

Samples at a glance
1 country
Age
unknown190
Country
CN190
Body site
primary190
Collected 2022–2023
2022: 111 samples2023: 79 samples20222023
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 25 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 165 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 11.46 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

24 of 87 people sampled more than once (48 samples; median 2, up to 2 per person). Schedule stated by the source: “Subset of 24 infected patients resampled after deworming treatment; no specific timepoints stated” (time origin: intervention_start).

How longitudinal and relatedness information is derived

Community composition
Faecalibacterium 22.4%Prevotella 8.1%Roseburia 6.8%Gemmiger 5.1%Phocaeicola 2.5%Ruminococcoides 2.5%Bifidobacterium 2.3%Megamonas 2.3%Blautia_A 2.2%Mediterraneibacter 2.0%Bacteroides 1.8%Collinsella 1.8%not assigned to a genus 4.4%other genera 35.9%

Genera, mean relative abundance over 174 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country190 100%190
health_condition0 0%
subject_id111 58%111
antibiotic_exposure190 100%190
collection_date190 100%190
detailed_location190 100%
health_condition_detail190 100%190
location_locality190 100%190
timepoint_label74 39%74
Papers (1)
Details
Archive description

Human fecal samples of Taeniasis asiatica infected patients and healthy controls

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.72. Assay shotgun_dna.

  • host study.title · “Human fecal samples Metagenome”
  • body site study.description · “Human fecal samples of Taeniasis”
  • body site run.scientific_name · “gut metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN44409411antibiotic_exposurenoR30.70paper.fulltext.methodstaken antibiotics or antifungal medications within the last 3 months were excluded
SAMN44409411collection_date2023-11R10.90biosample.attribute:collection_date2023-11
SAMN44409411countryCNR10.90sample.attr.geo_loc_nameChina:Dali
SAMN44409411health_condition_detailmixed_case_control: Taenia asiatica infection vs. healthy controlsR40.40study.descriptionTaeniasis asiatica infected patients and healthy controls
SAMN44409411location_localityDaliR10.85biosample.attribute:geo_loc_nameChina:Dali
SAMN44409431subject_idT1R10.70sample.name_rule:aliasT1
SAMN44409468timepoint_labelbaseline (pre-deworming)R10.70sample.name_rule:aliasT43be
Sequencing

190 runs over 190 samples · mean 11.68 Gbp per run (median 11.46 Gbp, total 2,218.76 Gbp; 190 runs with a base count) · layout PAIRED 190 · platform ILLUMINA 190 · models Illumina NovaSeq 6000 (190) · 92% of runs with a Sandpiper profile · first public 2024-10-27

Authors (13)

Mu W first · Ma P · Wang Y · Li Y · Ding Y · Zou Y · Pu L · Yan Q · Kong H · Guo X · Guo A · Li H · Wang S last

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata

Downloads

PRJNA1148078.csv.gz (5.5 KB) · parquet (77.2 KB) — all 190 samples, every field with route and confidence · PRJNA1148078_determinations.csv.gz (8.9 KB) — 1,135 evidence rows

Samples (190 · every field this project has values for · hover a cell for its source)
Loading the sample table…