Naoxintong plus atorvastatin for hyperlipidemia, Foshan, China
64 gut microbiome samples from adults (and 2 elderly) in Foshan, China, with cardiometabolic conditions, studying addition of Naoxintong capsule to atorvastatin drug therapy in an intervention design. machine-written summary
64 samples · 64 runs · CN · Adult · 2024 · 0.21 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 256 sample values (age, country, location locality, sex) |
| ✓ Abstract / description | 128 sample values (health condition, health condition detail) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Non-antibiotic pharmaceutical given as the study intervention (metformin design non_randomized_controlled · population cardiometabolic_other · Naoxintong capsule added to atorvastatin for hyperlipidemia
“addition of Naoxintong capsule to atorvastatin” — study.title (study level; per-sample arms are in the intervention column below)
longitudinal — not resolved
Schedule stated by the source: “12-week intervention trial (atorvastatin vs. atorvastatin+NXT)” (time origin: intervention/treatment start); stated follow-up 3 mo.
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 64 | 100% | ||||
| country | 64 | 100% | 64 | |||
| health_condition | 64 | 100% | 64 | |||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 64 | 100% | 64 | |||
| detailed_location | 64 | 100% | ||||
| health_condition_detail | 64 | 100% | 64 | |||
| location_locality | 64 | 100% | 64 | |||
| sex | 64 | 100% | 64 |
- Gut microbiome-metabolomics integration explores the adjunctive effect of Naoxintong capsule on atorvastatin in ameliorating hyperlipidemia: A randomized controlled pilot study. 2026 PMID 41544465 own_data
Archive description
To investigate the impact of the addition of Naoxintong capsule to statin therapy in patients with hyperlipidemia, including the change of gut microbiota.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “Integrated gut microbiome and metabolomics”
- body site study.description · “the change of gut microbiota.”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN43296255 | age_at_collection_days | 19358.2 | R1 | 0.70 | sample.attr.age | 53 |
| SAMN43296255 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China:Foshan |
| SAMN43296255 | health_condition | cardiometabolic_other | R4 | 0.50 | paper.abstract | Thirty-two hyperlipidemia patients were randomly divided into two groups |
| SAMN43296255 | health_condition_detail | hyperlipidemia | R4 | 0.50 | paper.abstract | Thirty-two hyperlipidemia patients were randomly divided into two groups |
| SAMN43296255 | location_locality | Foshan | R1 | 0.85 | biosample.attribute:geo_loc_name | China:Foshan |
| SAMN43296255 | sex | male | R1 | 0.90 | sample.attr.sex | male |
Sequencing
64 runs over 64 samples · mean 0.22 Gbp per run (median 0.21 Gbp, total 14.40 Gbp; 64 runs with a base count) · layout SINGLE 64 · platform ILLUMINA 64 · models Illumina HiSeq 2500 (64) · 0% of runs with a Sandpiper profile · first public 2024-08-24 – 2024-08-25
Authors (0)
No author record.
Downloads
PRJNA1150764.csv.gz (2.5 KB) · parquet (72.3 KB) — all 64 samples, every field with route and confidence · PRJNA1150764_determinations.csv.gz (2.7 KB) — 384 evidence rows