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PRJNA1154919 SRP529812

Gut microbiota after acute ischemic stroke, Guangzhou

16s sequencing

61 fecal/mucosal 16S samples from adults in Guangzhou, China, examining gut microbiota changes, including Helicobacter and flagellated bacteria, after acute ischemic stroke, using a case-control design. machine-written summary

61 samples · 61 runs · CN · Adult · 2024 · 90.1 Mbp / sample

Sources
✓Sequence archive 183○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive183 sample values (collection date, country, location locality)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC11513850
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
adult61
Country
CN61
Body site
primary61
Collected 2022–2024
2022: 29 samples2023: 15 samples2024: 17 samples20222024
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 4 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 31 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 25 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 1 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.09 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category61 100%
country61 100%61
health_condition0 0%
subject_id0 0%
collection_date61 100%61
detailed_location61 100%
location_locality61 100%61
Papers (1)
  • Activated sympathetic nerve post stroke downregulates Toll-like receptor 5 and disrupts the gut mucosal barrier. 2024 PMID 39383869 PMC11513850 own_data
Details
Archive description

The goal was to investigate the changes in the microbiota composition of fecal and mucosal microbiota after acute ischemic stroke.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.57. Assay shotgun_dna.

  • host study.description · “microbiota composition of fecal and mucosal microbiota”
  • body site study.description · “fecal and mucosal microbiota after acute ischemic stroke”
  • life stage study.description · “acute ischemic stroke”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN43436355collection_date2022-05-02R10.90biosample.attribute:collection_date2022-05-02
SAMN43436355countryCNR10.90sample.attr.geo_loc_nameChina: Guangzhou
SAMN43436355location_localityGuangzhouR10.85biosample.attribute:geo_loc_nameChina: Guangzhou
Sequencing

61 runs over 61 samples · mean 98.0 Mbp per run (median 90.1 Mbp, total 5.98 Gbp; 61 runs with a base count) · layout PAIRED 61 · platform ILLUMINA 61 · models Illumina HiSeq 2500 (61) · 0% of runs with a Sandpiper profile · first public 2024-09-01

Authors (15)

Wang H first · Li J · Wu G · Lin X · Chen J · Liang J · Zhang J · Luo X · Mao H · Xie J · Li Z · Zhou H · Xu K · Yin J · He Y last

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJNA1154919.csv.gz (2.2 KB) · parquet (70.8 KB) — all 61 samples, every field with route and confidence · PRJNA1154919_determinations.csv.gz (1.4 KB) — 183 evidence rows

Samples (61 · every field this project has values for · hover a cell for its source)
Loading the sample table…