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PRJNA1160072 SRP532245

Batch fermentation of gut samples from Crohn's disease patients

Chron fermentation

30 samples from Crohn's disease patients in Tucson, USA, studied using batch fermentation; no intervention or additional design details specified. machine-written summary

30 samples · 30 runs · US · Age unknown · 2024 · 8.77 Gbp / sample

Sources
✓Sequence archive 225○Abstract / description✓Full text 30✓Supplementary tables 75–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive225 sample values (collection date, country, health condition, health condition detail, latitude, location locality, longitude, subject id)
○ Abstract / descriptionread; no usable statement
✓ Full text30 sample values (location site) · PMC13625237
✓ Supplementary tables75 sample values (age, health condition, sex)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult27
unknown3
Condition
crohns_disease15
healthy_control15
Sex
male21
female9
Country
US30
Body site
primary30
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 23 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 7 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 8.77 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

10 of 10 people sampled more than once (30 samples; median 3, up to 3 per person).

How longitudinal and relatedness information is derived

Community composition
Veillonella 15.2%Escherichia 13.7%Bifidobacterium 12.7%Collinsella 5.1%Blautia_A 4.6%Bacteroides 4.2%Faecalibacterium 2.6%Phocaeicola 2.3%Ruminococcoides 1.7%Eubacterium 1.4%Roseburia 1.4%Gemmiger 1.4%not assigned to a genus 3.7%other genera 29.9%

Genera, mean relative abundance over 24 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category27 90%
country30 100%30
health_condition30 100%1515
subject_id30 100%30
age_at_collection_days30 100%30
collection_date30 100%30
detailed_location30 100%
health_condition_detail30 100%30
latitude30 100%30
location_locality30 100%30
location_site30 100%30
longitude30 100%30
sex30 100%30
Papers (1)
  • Fecal microbiota fermenting simple organic carbon substrates in vitro as microbial factories capable of distinguishing Crohn's disease from healthy states. 2026 PMID 42811337 PMC13625237 own_data
Details
Archive description

Batch fermentation of samples coming fro chron's disease patients

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.57. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.description · “Batch fermentation of samples coming fro chron's disease patients”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN43617871age_at_collection_days6939.75R20.80paper.supp.12934_2026_3052_MOESM3_ESM.xlsx[mapping_file!patient age]19
SAMN43617871collection_date2018-02-02R10.90biosample.attribute:collection_date2018-02-02
SAMN43617871countryUSR10.90sample.attr.geo_loc_nameUSA: Tucson
SAMN43617876health_conditioncrohns_diseaseR10.85biosample.attribute:host_phenotypeCD1
SAMN43617871health_conditionhealthy_controlR20.80paper.supp.12934_2026_3052_MOESM3_ESM.xlsx[mapping_file!diagnosis]healthy
SAMN43617871health_condition_detailH1R10.90sample.attr.host_phenotypeH1
SAMN43617871latitude32.2540R10.90biosample.attribute:lat_lon32.2540 N 110.9742 W
SAMN43617871location_localityTucsonR10.85biosample.attribute:geo_loc_nameUSA: Tucson
SAMN43617871location_siteCentre for Comprehensive Treatment of Inflammatory Bowel Diseases, Clinical Regional Hospital No. 2R30.70paper.fulltext.methodsCentre for Comprehensive Treatment of Inflammatory Bowel Diseases, Department of Gastroenterology
SAMN43617871longitude-110.9742R10.90biosample.attribute:lat_lon32.2540 N 110.9742 W
SAMN43617871sexmaleR20.80paper.supp.12934_2026_3052_MOESM3_ESM.xlsx[mapping_file!patient sex]M
SAMN43617871subject_idH1R10.85sample.attr.host_subject_idH1
Sequencing

30 runs over 30 samples · mean 8.56 Gbp per run (median 8.77 Gbp, total 256.69 Gbp; 30 runs with a base count) · layout PAIRED 30 · platform ILLUMINA 30 · models Illumina NovaSeq 6000 (30) · 80% of runs with a Sandpiper profile · first public 2024-09-15 – 2024-09-18

Authors (0)

No author record.

Downloads

PRJNA1160072.csv.gz (1.9 KB) · parquet (72.4 KB) — all 30 samples, every field with route and confidence · PRJNA1160072_determinations.csv.gz (3.2 KB) — 330 evidence rows

Samples (30 · every field this project has values for · hover a cell for its source)
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